ABCC13 multidrug resistance-associated protein 11 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: ABCC13
Official Full Name: multidrug resistance-associated protein 11
Primary source: TAIR:AT2G07680
Locus tag: AT2G07680
See related: Araport:AT2G07680
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: AtABCC13; ATMRP11; ATP-binding cassette C13; MRP11; multidrug resistance-associated protein 11
Summary: Encodes ABCC13/MRP11, a member of the multidrug resistance associated protein MRP/ABCC subfamily. Its expression is induced by gibberellic acid and downregulated by naphthalene acetic acid, abscisic acid, and zeatin.
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Genomic context

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See ABCC13 in Genome Data Viewer

Location:: chromosome: 2

Exon count:: 33

Sequence:: Chromosome: 2; NC_003071.7 (3514668..3522658)

Chromosome 2 - NC_003071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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NM_001335348.1

Supported by ESTs:

NM_001335349.1

Supported by ESTs:

NM_126770.8

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables ABC-type transporter activity	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables ATPase-coupled transmembrane transporter activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in extracellular region	ISM Inferred from Sequence Model more info
located_in plant-type vacuole	HDA more info	PubMed

General protein information

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Preferred Names: multidrug resistance-associated protein 11

NP_178811.7

multidrug resistance-associated protein 11 (MRP11); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: transport, transmembrane transport; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: multidrug resistance-associated protein 2 (TAIR:AT2G34660.2); Has 539195 Blast hits to 324792 proteins in 3896 species: Archae - 9326; Bacteria - 437824; Metazoa - 12258; Fungi - 6863; Plants - 5577; Viruses - 6; Other Eukaryotes - 67341 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003071.7 Reference assembly

Range

3514668..3522658

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001335345.1 → NP_001323939.1 multidrug resistance-associated protein 11 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A178U749, A0A1P8AYP5
NM_001335346.1 → NP_001323940.1 multidrug resistance-associated protein 11 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1P8AYK9, A0A5S9XQ57, A0A654ESC7
NM_001335347.1 → NP_001323936.1 multidrug resistance-associated protein 11 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1P8AYI4, A0A654ESC7
NM_126770.8 → NP_178811.7 multidrug resistance-associated protein 11 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_178811.7

Status: REVIEWED

UniProtKB/Swiss-Prot

F4INF8, Q9SKX0

Conserved Domains (4) summary

cd03244
Location:1166 → 1385

ABCC_MRP_domain2; ATP-binding cassette domain 2 of multidrug resistance-associated protein

cd03250
Location:558 → 762

ABCC_MRP_domain1; ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C

TIGR01271
Location:192 → 1393

CFTR_protein; cystic fibrosis transmembrane conductor regulator (CFTR)

cl00549
Location:865 → 1121

ABC_membrane; ABC transporter transmembrane region
NM_001335348.1 → NP_001323937.1 multidrug resistance-associated protein 11 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/Swiss-Prot

F4INF8, Q9SKX0

UniProtKB/TrEMBL

A0A1P8AYL1
NM_001335349.1 → NP_001323938.1 multidrug resistance-associated protein 11 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1P8AYJ8, A0A5S9XQ57