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    MIZ1 MIZU-KUSSEI-like protein (Protein of unknown function, DUF617) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818764, updated on 18-Sep-2024

    Summary

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    Official Symbol
    MIZ1
    Official Full Name
    MIZU-KUSSEI-like protein (Protein of unknown function, DUF617)
    Primary source
    TAIR:AT2G41660
    Locus tag
    AT2G41660
    See related
    Araport:AT2G41660
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    mizu-kussei 1; T32G6.18; T32G6_18
    Summary
    Essential for hydrotropism in roots. Mutant roots are defective in hydrotropism, and have slightly reduced phototropism and modified wavy growth response. Has normal gravitropism and root elongation.
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    Genomic context

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    See MIZ1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    1
    Sequence:
    Chromosome: 2; NC_003071.7 (17367492..17369206)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Glycosyltransferase family 61 protein Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene NADPH-dependent thioredoxin reductase C

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Recovery of root hydrotropism in miz1 mutant by eliminating root gravitropism. Li Y, et al. J Plant Physiol, 2024 Jan. PMID 38104389
    2. MIZ1-regulated hydrotropism functions in the growth and survival of Arabidopsis thaliana under natural conditions. Iwata S, et al. Ann Bot, 2013 Jul. PMID 23658369, Free PMC Article
    3. Overexpression of MIZU-KUSSEI1 enhances the root hydrotropic response by retaining cell viability under hydrostimulated conditions in Arabidopsis thaliana. Miyazawa Y, et al. Plant Cell Physiol, 2012 Nov. PMID 23012350
    4. MIZ1, an essential protein for root hydrotropism, is associated with the cytoplasmic face of the endoplasmic reticulum membrane in Arabidopsis root cells. Yamazaki T, et al. FEBS Lett, 2012 Feb 17. PMID 22285304
    5. A gene essential for hydrotropism in roots. Kobayashi A, et al. Proc Natl Acad Sci U S A, 2007 Mar 13. PMID 17360591, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Recovery of root hydrotropism in miz1 mutant by eliminating root gravitropism.
      Title: Recovery of root hydrotropism in miz1 mutant by eliminating root gravitropism.
    2. MIZ1 acts downstream of PGM1 in regulating root hydrotropism.
      Title: MIZ1 acts downstream of PGM1 in regulating root hydrotropism.
    3. MIZU-KUSSEI1 (MIZ1) and GNOM/MIZ2 control not only positive hydrotropism but also phototropism in Arabidopsis roots.
      Title: MIZU-KUSSEI1 (MIZ1) and GNOM/MIZ2 control not only positive hydrotropism but also phototropism in Arabidopsis roots.
    4. the inhibition of ECA1 by MIZ1 changes the balance between cytosolic Ca(2+) influx and efflux and generates the cytosolic Ca(2+) signal required for water tracking.
      Title: MIZ1 regulates ECA1 to generate a slow, long-distance phloem-transmitted Ca(2+) signal essential for root water tracking in Arabidopsis.
    5. MIZ1-regulated hydrotropism functions in the growth and survival of Arabidopsis thaliana
      Title: MIZ1-regulated hydrotropism functions in the growth and survival of Arabidopsis thaliana under natural conditions.
    6. Overexpression of MIZ1 enhances tolerance to osmotic stress.
      Title: Overexpression of MIZU-KUSSEI1 enhances the root hydrotropic response by retaining cell viability under hydrostimulated conditions in Arabidopsis thaliana.
    7. MIZ1-GFP was detected at high levels in cortical cells and lateral root cap cells and accumulated in compartments in cortical cells.
      Title: MIZ1, an essential protein for root hydrotropism, is associated with the cytoplasmic face of the endoplasmic reticulum membrane in Arabidopsis root cells.
    8. MIZ1 plays a role in lateral root development by maintaining auxin levels and its function requires GNOM activity.
      Title: Hormonal regulation of lateral root development in Arabidopsis modulated by MIZ1 and requirement of GNOM activity for MIZ1 function.
    9. MIZ1 functions in the early phase of the hydrotropic response in Arabidopsis [MIZ1]
      Title: A gene essential for hydrotropism in roots.
    Submit: New GeneRIF Correction

    General gene information

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    NM_129729.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within chloroplast organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within hydrotropism IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in hydrotropism IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cortical endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endoplasmic reticulum membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    MIZU-KUSSEI-like protein (Protein of unknown function, DUF617)
    NP_565953.1
    • mizu-kussei 1 (MIZ1); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF617, plant (InterPro:IPR006460); BEST Arabidopsis thaliana protein match is: Protein of unknown function, DUF617 (TAIR:AT3G25640.1); Has 258 Blast hits to 256 proteins in 14 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 258; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      17367492..17369206
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129729.3 → NP_565953.1  MIZU-KUSSEI-like protein (Protein of unknown function, DUF617) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565953.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22227, Q8LB38
      UniProtKB/TrEMBL
      A0A178VY97, A0A5S9X672
      Conserved Domains (1) summary
      TIGR01570
      Location:129 → 297
      A_thal_3588; uncharacterized plant-specific domain TIGR01570
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O22227.1

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