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    emb2458 FtsH extracellular protease family [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819589, updated on 18-Sep-2024

    Summary

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    Official Symbol
    emb2458
    Official Full Name
    FtsH extracellular protease family
    Primary source
    TAIR:AT3G04340
    Locus tag
    AT3G04340
    See related
    Araport:AT3G04340
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    embryo defective 2458; T6K12.4; T6K12_4
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    Genomic context

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    See emb2458 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    16
    Sequence:
    Chromosome: 3; NC_003074.8 (1146568..1153650, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Kunitz family trypsin and protease inhibitor protein Neighboring gene Kunitz family trypsin and protease inhibitor protein Neighboring gene vacuolar sorting-associated protein (DUF946) Neighboring gene Calcium-dependent lipid-binding (CaLB domain) family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Impairment of FtsHi5 Function Affects Cellular Redox Balance and Photorespiratory Metabolism in Arabidopsis. Wang T, et al. Plant Cell Physiol, 2018 Dec 1. PMID 30137570
    2. A Ycf2-FtsHi Heteromeric AAA-ATPase Complex Is Required for Chloroplast Protein Import. Kikuchi S, et al. Plant Cell, 2018 Nov. PMID 30309901, Free PMC Article
    3. Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis. Froehlich JE, et al. J Proteome Res, 2003 Jul-Aug. PMID 12938931
    4. AT_CHLORO, a comprehensive chloroplast proteome database with subplastidial localization and curated information on envelope proteins. Ferro M, et al. Mol Cell Proteomics, 2010 Jun. PMID 20061580, Free PMC Article
    5. Arabidopsis plasmodesmal proteome. Fernandez-Calvino L, et al. PLoS One, 2011 Apr 20. PMID 21533090, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. FtsHi5 functions in maintaining the cellular redox balance and thus regulates photorespiratory metabolism.[FtsHi5]
      Title: Impairment of FtsHi5 Function Affects Cellular Redox Balance and Photorespiratory Metabolism in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    NM_111305.7

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP-dependent peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables chloroplast protein-transporting ATPase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell redox homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within chloroplast organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within embryo development ending in seed dormancy NAS
    Non-traceable Author Statement
    more info
    		  
    acts_upstream_of_or_within protein import into chloroplast stroma IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of photorespiration IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Ycf2/FtsHi complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast envelope HDA PubMed 
    colocalizes_with chloroplast envelope IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast inner membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    FtsH extracellular protease family
    NP_187084.6
    • embryo defective 2458 (emb2458); FUNCTIONS IN: nucleoside-triphosphatase activity, ATPase activity, metalloendopeptidase activity, nucleotide binding, ATP binding; INVOLVED IN: embryo development ending in seed dormancy; LOCATED IN: chloroplast, chloroplast envelope; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA-type, core (InterPro:IPR003959), ATPase, AAA+ type, core (InterPro:IPR003593), Peptidase M41 (InterPro:IPR000642); BEST Arabidopsis thaliana protein match is: FTSH protease 1 (TAIR:AT1G50250.1); Has 32899 Blast hits to 29484 proteins in 3073 species: Archae - 1598; Bacteria - 9893; Metazoa - 6215; Fungi - 3644; Plants - 2880; Viruses - 25; Other Eukaryotes - 8644 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      1146568..1153650 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111305.7 → NP_187084.6  FtsH extracellular protease family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187084.6

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4J3N2, Q9M8Z0
      UniProtKB/TrEMBL
      A0A178VGJ4
      Conserved Domains (4) summary
      smart00382
      Location:817 → 956
      AAA; ATPases associated with a variety of cellular activities
      pfam00004
      Location:820 → 952
      AAA; ATPase family associated with various cellular activities (AAA)
      pfam01434
      Location:1102 → 1276
      Peptidase_M41; Peptidase family M41
      cl00240
      Location:231 → 295
      RRF; Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation. Thus ribosomes are "recycled" and ready for another round of ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4J3N2.1

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