GTF2H2 general transcription factor II H2 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Go to the top of the page Help

Official Symbol: GTF2H2
Official Full Name: general transcription factor II H2
Primary source: TAIR:AT1G05055
Locus tag: AT1G05055
See related: Araport:AT1G05055
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: AT1G05050; ATGTF2H2; general transcription factor II H2
Summary: Member of transcription factor TFIIH complex. Involved in transcription and DNA repair and interacts with AtXPD.
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See GTF2H2 in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 4

Sequence:: Chromosome: 1; NC_003070.9 (1448631..1450901, complement)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

AtGTF2H2 can act in transcription and nucleotide excision repair(NER), and it participates in both processes in Arabidopsis as part of TFIIH. [AtGTF2H2]
Title: Arabidopsis homologue of human transcription factor IIH/nucleotide excision repair factor p44 can function in transcription and DNA repair and interacts with AtXPD.

Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

MASC_STS14611 (e-PCR)
- UniSTS:258730

Homology

Orthologs from OrthoDB

NM_148434.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in DNA-templated transcription	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within nucleotide-excision repair	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within regulation of transcription by RNA polymerase II	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	ISM Inferred from Sequence Model more info
part_of transcription factor TFIIH core complex	IEA Inferred from Electronic Annotation more info
part_of transcription factor TFIIH holo complex	IGI Inferred from Genetic Interaction more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: general transcription factor II H2

NP_683275.2

general transcription factor II H2 (GTF2H2); CONTAINS InterPro DOMAIN/s: Ssl1-like (InterPro:IPR007198), TFIIH basal transcription factor complex, subunit SSL1 (InterPro:IPR012170), Zinc finger, RING-type (InterPro:IPR001841), TFIIH C1-like, C-terminal (InterPro:IPR004595), von Willebrand factor, type A (InterPro:IPR002035); Has 470 Blast hits to 463 proteins in 203 species: Archae - 0; Bacteria - 0; Metazoa - 183; Fungi - 160; Plants - 39; Viruses - 0; Other Eukaryotes - 88 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

1448631..1450901 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_148434.4 → NP_683275.2 general transcription factor II H2 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_683275.2

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9ZVN9

UniProtKB/TrEMBL

A0A097PR03, A0A178W5Z7, A0A5S9SPA7

Conserved Domains (1) summary

COG5151
Location:26 → 411

SSL1; RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit SSL1 [Transcription / DNA replication, recombination, and repair]