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    ERG28 ergosterol biosynthesis protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837538, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ERG28
    Official Full Name
    ergosterol biosynthesis protein
    Primary source
    TAIR:AT1G10030
    Locus tag
    AT1G10030
    See related
    Araport:AT1G10030
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    homolog of yeast ergosterol28; T27I1.5; T27I1_5
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    Genomic context

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    See ERG28 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (3273753..3275953)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene amino acid permease 8 Neighboring gene formin-like protein (DUF1005) Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene glycosyl hydrolase family 10 protein / carbohydrate-binding domain-containing protein Neighboring gene branched-chain amino acid transaminase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis ERG28 tethers the sterol C4-demethylation complex to prevent accumulation of a biosynthetic intermediate that interferes with polar auxin transport. Mialoundama AS, et al. Plant Cell, 2013 Dec. PMID 24326590, Free PMC Article
    2. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    3. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ERG28 is required for polar auxin transport in plants.
      Title: Arabidopsis ERG28 tethers the sterol C4-demethylation complex to prevent accumulation of a biosynthetic intermediate that interferes with polar auxin transport.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_100877.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein-macromolecule adaptor activity IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of auxin polar transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ergosterol biosynthesis protein
    NP_563858.1
    • homolog of yeast ergosterol28 (ERG28); INVOLVED IN: biological_process unknown; LOCATED IN: endomembrane system, integral to membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Erg28-like (InterPro:IPR005352); Has 223 Blast hits to 223 proteins in 105 species: Archae - 0; Bacteria - 0; Metazoa - 67; Fungi - 94; Plants - 48; Viruses - 0; Other Eukaryotes - 14 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      3273753..3275953
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100877.3 → NP_563858.1  ergosterol biosynthesis protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_563858.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80594, Q7Y031
      UniProtKB/TrEMBL
      A0A178WJ70, A0A5S9TJT6, Q8LEN5
      Conserved Domains (1) summary
      pfam03694
      Location:3 → 97
      Erg28; Erg28 like protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O80594.2

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