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    ASP4 aspartate aminotransferase 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842579, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ASP4
    Official Full Name
    aspartate aminotransferase 4
    Primary source
    TAIR:AT1G62800
    Locus tag
    AT1G62800
    See related
    Araport:AT1G62800
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    aspartate aminotransferase 4; ASPARTATE AMINOTRANSFERASE 4; F23N19.17; F23N19_17
    Summary
    Encodes aspartate aminotransferase (Asp4).
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    Genomic context

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    See ASP4 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    12
    Sequence:
    Chromosome: 1; NC_003070.9 (23253703..23257546, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene dimethylallyl, adenosine tRNA methylthiotransferase Neighboring gene Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Copper amine oxidase family protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The aspartate aminotransferase gene family of Arabidopsis encodes isoenzymes localized to three distinct subcellular compartments. Schultz CJ, et al. Plant J, 1995 Jan. PMID 7894512
    2. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    3. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_001334052.1
    NM_104958.2
    NM_179507.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables L-aspartate:2-oxoglutarate aminotransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables L-aspartate:2-oxoglutarate aminotransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in 2-oxoglutarate metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in amino acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in aspartate metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in glutamate metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    aspartate aminotransferase 4
    NP_564803.1
    • aspartate aminotransferase 4 (ASP4); FUNCTIONS IN: pyridoxal phosphate binding, transferase activity, transferring nitrogenous groups, transaminase activity, catalytic activity; INVOLVED IN: asparagine catabolic process, biosynthetic process, glutamate catabolic process to oxaloacetate, cellular amino acid metabolic process, aspartate transamidation; LOCATED IN: cytosol; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Aminotransferase, class I/classII (InterPro:IPR004839), Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Aminotransferases, class-I, pyridoxal-phosphate-binding site (InterPro:IPR004838), Aspartate/other aminotransferase (InterPro:IPR000796), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421); BEST Arabidopsis thaliana protein match is: aspartate aminotransferase 2 (TAIR:AT5G19550.1); Has 5933 Blast hits to 5926 proteins in 1472 species: Archae - 1; Bacteria - 3981; Metazoa - 484; Fungi - 405; Plants - 397; Viruses - 0; Other Eukaryotes - 665 (source: NCBI BLink).
    NP_849838.1
    • aspartate aminotransferase 4 (ASP4); FUNCTIONS IN: transferase activity, transferring nitrogenous groups, pyridoxal phosphate binding, transaminase activity, catalytic activity; INVOLVED IN: biosynthetic process, cellular amino acid metabolic process; LOCATED IN: cytosol; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Aminotransferase, class I/classII (InterPro:IPR004839), Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Aminotransferases, class-I, pyridoxal-phosphate-binding site (InterPro:IPR004838), Aspartate/other aminotransferase (InterPro:IPR000796), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421); BEST Arabidopsis thaliana protein match is: aspartate aminotransferase 2 (TAIR:AT5G19550.1); Has 5813 Blast hits to 5806 proteins in 1432 species: Archae - 0; Bacteria - 3885; Metazoa - 484; Fungi - 405; Plants - 390; Viruses - 0; Other Eukaryotes - 649 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      23253703..23257546 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_179507.2 → NP_849838.1  aspartate aminotransferase 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849838.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WGW2, A0A5S9WRR3, A0A654EKG9, F4I0D4
      Conserved Domains (2) summary
      PLN02397
      Location:1 → 404
      PLN02397; aspartate transaminase
      pfam00155
      Location:29 → 397
      Aminotran_1_2; Aminotransferase class I and II

    2. NM_104958.2 → NP_564803.1  aspartate aminotransferase 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564803.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P46646, Q9SI69
      UniProtKB/TrEMBL
      A0A178WGW2, A0A5S9WRR3, A0A654EKG9
      Conserved Domains (2) summary
      PLN02397
      Location:1 → 402
      PLN02397; aspartate transaminase
      pfam00155
      Location:29 → 395
      Aminotran_1_2; Aminotransferase class I and II

    3. NM_001334052.1 → NP_001321076.1  aspartate aminotransferase 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WIS3, A0A1P8APT9
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P46646.2

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