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    5PTASE11 inositol polyphosphate 5-phosphatase 11 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841160, updated on 18-Sep-2024

    Summary

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    Official Symbol
    5PTASE11
    Official Full Name
    inositol polyphosphate 5-phosphatase 11
    Primary source
    TAIR:AT1G47510
    Locus tag
    AT1G47510
    See related
    Araport:AT1G47510
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA INOSITOL POLYPHOSPHATE 5-PHOSPHATASE 11; AT5PTASE11; F16N3.22; F16N3_22; inositol polyphosphate 5-phosphatase 11
    Summary
    Encodes a phosphatidylinositol polyphosphate 5-phosphatase. It can dephosphorylate PI(4,5)P2, PI(3,5)P2, and PI(3,4,5)P3, but, it is not active against PI(5)P or the water soluble inositol(1,4,5)P3 or inositol(1,3,4,5)P4. The transcript levels for this gene rise in response to auxin, ABA, and JA.
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    Genomic context

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    See 5PTASE11 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (17435525..17438490, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Polynucleotidyl transferase, ribonuclease H-like superfamily protein Neighboring gene RNA-binding protein 47C' Neighboring gene ncRNA Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A phosphatidylinositol phosphate-specific myo-inositol polyphosphate 5-phosphatase required for seedling growth. Ercetin ME, et al. Plant Mol Biol, 2008 Jul. PMID 18392779
    2. Molecular characterization of an Arabidopsis gene encoding a phospholipid-specific inositol polyphosphate 5-phosphatase. Ercetin ME, et al. Plant Physiol, 2004 Jun. PMID 15181205, Free PMC Article
    3. Inositol polyphosphate 5-phosphatase7 regulates the production of reactive oxygen species and salt tolerance in Arabidopsis. Kaye Y, et al. Plant Physiol, 2011 Sep. PMID 21677096, Free PMC Article
    4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001333275.1
    NM_103644.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within phosphatidylinositol dephosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in phosphatidylinositol dephosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in phosphatidylinositol dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to abscisic acid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to auxin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to jasmonic acid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in response to salt stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    inositol polyphosphate 5-phosphatase 11
    NP_001185162.1
    • inositol polyphosphate 5-phosphatase 11 (5PTASE11); CONTAINS InterPro DOMAIN/s: Inositol polyphosphate related phosphatase (InterPro:IPR000300), Endonuclease/exonuclease/phosphatase (InterPro:IPR005135); BEST Arabidopsis thaliana protein match is: Endonuclease/exonuclease/phosphatase family protein (TAIR:AT1G65580.1).
    NP_175182.2
    • inositol polyphosphate 5-phosphatase 11 (5PTASE11); FUNCTIONS IN: hydrolase activity, phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity, phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; INVOLVED IN: response to jasmonic acid stimulus, response to auxin stimulus, N-terminal protein myristoylation, phosphoinositide dephosphorylation, response to abscisic acid stimulus; EXPRESSED IN: shoot, rosette leaf, cauline leaf, flower, root; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: Inositol polyphosphate related phosphatase (InterPro:IPR000300), Endonuclease/exonuclease/phosphatase (InterPro:IPR005135); BEST Arabidopsis thaliana protein match is: Endonuclease/exonuclease/phosphatase family protein (TAIR:AT1G65580.1); Has 2052 Blast hits to 2006 proteins in 223 species: Archae - 0; Bacteria - 0; Metazoa - 723; Fungi - 525; Plants - 524; Viruses - 0; Other Eukaryotes - 280 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      17435525..17438490 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001333274.1 → NP_001322725.1  inositol polyphosphate 5-phosphatase 11 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AUV8

    2. NM_001198233.1 → NP_001185162.1  inositol polyphosphate 5-phosphatase 11 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001185162.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W7T2, F4HT96
      Conserved Domains (1) summary
      cl00490
      Location:149 → 263
      EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

    3. NM_103644.3 → NP_175182.2  inositol polyphosphate 5-phosphatase 11 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175182.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q5EAF2, Q9SX81
      UniProtKB/TrEMBL
      A0A178W7T2
      Conserved Domains (1) summary
      cl00490
      Location:56 → 325
      EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

    4. NM_001333275.1 → NP_001322726.1  inositol polyphosphate 5-phosphatase 11 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W7T2, A0A1P8AUX2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5EAF2.1

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