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    ATF1 activating transcription factor 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 506967, updated on 27-Dec-2024

    Summary

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    Official Symbol
    ATF1provided by VGNC
    Official Full Name
    activating transcription factor 1provided by VGNC
    Primary source
    VGNC:VGNC:26239
    See related
    BGD:BT11870; Ensembl:ENSBTAG00000018131
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See ATF1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (29107516..29171842, complement)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene ZW10 interactor-like Neighboring gene large ribosomal subunit protein uL22-like Neighboring gene transmembrane serine protease 12 Neighboring gene transfer RNA glycine (anticodon UCC) Neighboring gene disco interacting protein 2 homolog B Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene histone H4-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Regulation of ATF1 and ATF2 transcripts by sequences in their 3' untranslated region in cleavage-stage cattle embryos. Orozco-Lucero E, et al. Mol Reprod Dev, 2017 Apr. PMID 28198054
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC143110

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of ATF4-CREB1 transcription factor complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cyclic AMP-dependent transcription factor ATF-1
    Names
    cAMP-dependent transcription factor ATF-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075289.1 → NP_001068757.1  cyclic AMP-dependent transcription factor ATF-1

      See identical proteins and their annotated locations for NP_001068757.1

      Status: PROVISIONAL

      Source sequence(s)
      BC123855
      UniProtKB/Swiss-Prot
      Q08DA8
      Related
      ENSBTAP00000024135.4, ENSBTAT00000024135.5
      Conserved Domains (2) summary
      cd14690
      Location:214 → 268
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:48 → 82
      pKID; pKID domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      29107516..29171842 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010804952.4 → XP_010803254.1  cyclic AMP-dependent transcription factor ATF-1 isoform X2

      See identical proteins and their annotated locations for XP_010803254.1

      UniProtKB/TrEMBL
      A0AAA9S322
      Conserved Domains (2) summary
      cd14690
      Location:254 → 308
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:88 → 122
      pKID; pKID domain

    2. XM_024991502.2 → XP_024847270.1  cyclic AMP-dependent transcription factor ATF-1 isoform X3

      Conserved Domains (2) summary
      cd14690
      Location:246 → 300
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:80 → 114
      pKID; pKID domain

    3. XM_005206278.5 → XP_005206335.2  cyclic AMP-dependent transcription factor ATF-1 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LN51, A0AAA9S2P8
      Related
      ENSBTAP00000077572.1, ENSBTAT00000119597.1
      Conserved Domains (2) summary
      cd14690
      Location:316 → 370
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:150 → 184
      pKID; pKID domain

    4. XM_010804955.4 → XP_010803257.1  cyclic AMP-dependent transcription factor ATF-1 isoform X2

      See identical proteins and their annotated locations for XP_010803257.1

      UniProtKB/TrEMBL
      A0AAA9S322
      Related
      ENSBTAP00000078150.1, ENSBTAT00000099877.1
      Conserved Domains (2) summary
      cd14690
      Location:254 → 308
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:88 → 122
      pKID; pKID domain

    5. XM_010804953.4 → XP_010803255.1  cyclic AMP-dependent transcription factor ATF-1 isoform X2

      See identical proteins and their annotated locations for XP_010803255.1

      UniProtKB/TrEMBL
      A0AAA9S322
      Conserved Domains (2) summary
      cd14690
      Location:254 → 308
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:88 → 122
      pKID; pKID domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08DA8.1 GenPept UniProtKB/Swiss-Prot:Q08DA8

    Gene LinkOut

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