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    TIA1 TIA1 cytotoxic granule associated RNA binding protein [ Bos taurus (domestic cattle) ]

    Gene ID: 538533, updated on 30-Jan-2025

    Summary

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    Official Symbol
    TIA1provided by VGNC
    Official Full Name
    TIA1 cytotoxic granule associated RNA binding proteinprovided by VGNC
    Primary source
    VGNC:VGNC:35858
    See related
    BGD:BT17771; EnsemblRapid:ENSBTAG00070027348
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See TIA1 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 11 NC_037338.1 (68499876..68554928, complement)

    Chromosome 11 - NC_037338.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101905499 Neighboring gene poly(rC) binding protein 1 Neighboring gene chromosome 11 C2orf42 homolog Neighboring gene phagosome assembly factor 1-like Neighboring gene transfer RNA glycine (anticodon CCC) Neighboring gene prenylcysteine oxidase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037338.1 Chromosome 11 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC143006

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables mRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cytotoxic granule associated RNA binding protein TIA1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076109.1 → NP_001069577.1  cytotoxic granule associated RNA binding protein TIA1

      See identical proteins and their annotated locations for NP_001069577.1

      Status: PROVISIONAL

      Source sequence(s)
      BC120427
      UniProtKB/TrEMBL
      A0AAA9SM81, Q0VBZ6
      Related
      ENSBTAP00070037127.1, ENSBTAT00070062243.1
      Conserved Domains (4) summary
      cd12618
      Location:105 → 184
      RRM2_TIA1; RNA recognition motif 2 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
      cd12621
      Location:214 → 287
      RRM3_TIA1; RNA recognition motif 3 in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
      TIGR01661
      Location:6 → 280
      ELAV_HUD_SF; ELAV/HuD family splicing factor
      cl17169
      Location:8 → 81
      RRM_SF; RNA recognition motif (RRM) superfamily

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037338.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      68499876..68554928 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059891371.1 → XP_059747354.1  cytotoxic granule associated RNA binding protein TIA1 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1LP63

    2. XM_059891370.1 → XP_059747353.1  cytotoxic granule associated RNA binding protein TIA1 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LP63

    3. XM_024998933.2 → XP_024854701.2  cytotoxic granule associated RNA binding protein TIA1 isoform X10

      UniProtKB/TrEMBL
      A0A3Q1LP63

    4. XM_024998932.2 → XP_024854700.2  cytotoxic granule associated RNA binding protein TIA1 isoform X9

      UniProtKB/TrEMBL
      A0AAA9SM81

    5. XM_005212866.4 → XP_005212923.1  cytotoxic granule associated RNA binding protein TIA1 isoform X8

      See identical proteins and their annotated locations for XP_005212923.1

      UniProtKB/TrEMBL
      A0AAA9SM81
      Conserved Domains (3) summary
      cd12620
      Location:203 → 275
      RRM3_TIAR; RNA recognition motif 3 (RRM3) found in nucleolysin TIAR and similar proteins
      cd12615
      Location:8 → 81
      RRM1_TIA1; RNA recognition motif 1 (RRM1) found in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
      cd12618
      Location:93 → 170
      RRM2_TIA1; RNA recognition motif 2 (RRM2) found in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins

    6. XM_024998930.2 → XP_024854698.2  cytotoxic granule associated RNA binding protein TIA1 isoform X6

      UniProtKB/TrEMBL
      A0AAA9SM81

    7. XM_005212864.5 → XP_005212921.1  cytotoxic granule associated RNA binding protein TIA1 isoform X5

      See identical proteins and their annotated locations for XP_005212921.1

      UniProtKB/TrEMBL
      A0AAA9SM81
      Conserved Domains (3) summary
      cd12620
      Location:214 → 286
      RRM3_TIAR; RNA recognition motif 3 (RRM3) found in nucleolysin TIAR and similar proteins
      cd12615
      Location:8 → 81
      RRM1_TIA1; RNA recognition motif 1 (RRM1) found in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
      cd12618
      Location:104 → 181
      RRM2_TIA1; RNA recognition motif 2 (RRM2) found in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins

    8. XM_059891373.1 → XP_059747356.1  cytotoxic granule associated RNA binding protein TIA1 isoform X7

      UniProtKB/TrEMBL
      A0AAA9SM81
      Related
      ENSBTAP00070037105.1, ENSBTAT00070062218.1

    9. XM_024998929.2 → XP_024854697.2  cytotoxic granule associated RNA binding protein TIA1 isoform X4

      UniProtKB/TrEMBL
      A0AAA9SM81

    10. XM_005212862.5 → XP_005212919.1  cytotoxic granule associated RNA binding protein TIA1 isoform X3

      See identical proteins and their annotated locations for XP_005212919.1

      UniProtKB/TrEMBL
      A0AAA9SM81, A0AAA9SRD9
      Related
      ENSBTAP00070037096.1, ENSBTAT00070062204.1
      Conserved Domains (3) summary
      cd12620
      Location:216 → 288
      RRM3_TIAR; RNA recognition motif 3 (RRM3) found in nucleolysin TIAR and similar proteins
      cd12615
      Location:8 → 83
      RRM1_TIA1; RNA recognition motif 1 (RRM1) found in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
      cd12618
      Location:106 → 183
      RRM2_TIA1; RNA recognition motif 2 (RRM2) found in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins

    11. XM_024998940.2 → XP_024854708.1  cytotoxic granule associated RNA binding protein TIA1 isoform X11

      UniProtKB/TrEMBL
      A0AAA9TZF5
      Conserved Domains (2) summary
      cd12615
      Location:8 → 81
      RRM1_TIA1; RNA recognition motif 1 (RRM1) found in nucleolysin TIA-1 isoform p40 (p40-TIA-1) and similar proteins
      cl17169
      Location:104 → 133
      RRM_SF; RNA recognition motif (RRM) superfamily

    RNA

    1. XR_009496291.1 RNA Sequence

    2. XR_009496292.1 RNA Sequence

      Related
      ENSBTAT00070062174.1
    Nucleotide Protein Strain
    Heading Accession and Version

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