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    FOSB FosB proto-oncogene, AP-1 transcription factor subunit [ Bos taurus (domestic cattle) ]

    Gene ID: 540819, updated on 27-Dec-2024

    Summary

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    Official Symbol
    FOSBprovided by VGNC
    Official Full Name
    FosB proto-oncogene, AP-1 transcription factor subunitprovided by VGNC
    Primary source
    VGNC:VGNC:29074
    See related
    BGD:BT18637; Ensembl:ENSBTAG00000008182
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See FOSB in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (53074358..53081311)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene protein phosphatase 1 regulatory subunit 13 like Neighboring gene RNA polymerase I subunit G Neighboring gene ERCC excision repair 1, endonuclease non-catalytic subunit Neighboring gene uncharacterized LOC112442336 Neighboring gene transfer RNA opal suppressor (anticodon UCA) Neighboring gene reticulon 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC143206

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein FosB

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001102248.1 → NP_001095718.1  protein FosB

      See identical proteins and their annotated locations for NP_001095718.1

      Status: PROVISIONAL

      Source sequence(s)
      BC148047
      UniProtKB/TrEMBL
      A0AAF6DMA7, A6QLQ3, F1MGX1
      Related
      ENSBTAP00000010762.6, ENSBTAT00000010762.7
      Conserved Domains (1) summary
      cd14721
      Location:165 → 218
      bZIP_Fos; Basic leucine zipper (bZIP) domain of the oncogene Fos (Fos): a DNA-binding and dimerization domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      53074358..53081311
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059876884.1 → XP_059732867.1  protein FosB isoform X2

      UniProtKB/TrEMBL
      A0A3Q1M3Q6
      Related
      ENSBTAP00000068161.1, ENSBTAT00000084387.2

    2. XM_024978468.2 → XP_024834236.1  protein FosB isoform X1

      UniProtKB/TrEMBL
      A0AAA9TFB9
      Related
      ENSBTAP00000097274.1, ENSBTAT00000119667.1
      Conserved Domains (1) summary
      cl21462
      Location:150 → 182
      bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
    Nucleotide Protein Strain
    Heading Accession and Version

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