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    SAE1 SUMO1 activating enzyme subunit 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 505512, updated on 27-Dec-2024

    Summary

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    Official Symbol
    SAE1provided by VGNC
    Official Full Name
    SUMO1 activating enzyme subunit 1provided by VGNC
    Primary source
    VGNC:VGNC:34261
    See related
    BGD:BT15952; Ensembl:ENSBTAG00000002676
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    See SAE1 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (54170202..54232459)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene zinc finger CCCH-type containing 4 Neighboring gene uncharacterized LOC132342870 Neighboring gene uncharacterized LOC104974899 Neighboring gene BCL2 binding component 3 Neighboring gene coiled-coil domain containing 9

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC151535

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables SUMO activating enzyme activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein sumoylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of SUMO activating enzyme complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SUMO-activating enzyme subunit 1
    Names
    ubiquitin-like 1-activating enzyme E1A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081711.1 → NP_001075180.1  SUMO-activating enzyme subunit 1

      See identical proteins and their annotated locations for NP_001075180.1

      Status: PROVISIONAL

      Source sequence(s)
      BC133519
      UniProtKB/Swiss-Prot
      A2VE14
      Related
      ENSBTAP00000003467.4, ENSBTAT00000003467.6
      Conserved Domains (1) summary
      cd01492
      Location:16 → 341
      Aos1_SUMO; Ubiquitin activating enzyme (E1) subunit Aos1. Aos1 is part of the heterodimeric activating enzyme (E1), specific for the SUMO family of ubiquitin-like proteins (Ubls). E1 enzymes are part of a conjugation cascade to attach Ub or Ubls, covalently to ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      54170202..54232459
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005219191.5 → XP_005219248.1  SUMO-activating enzyme subunit 1 isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LQS3
      Related
      ENSBTAP00000062557.1, ENSBTAT00000075271.2
      Conserved Domains (1) summary
      cd01492
      Location:16 → 368
      Aos1_SUMO; Ubiquitin activating enzyme (E1) subunit Aos1. Aos1 is part of the heterodimeric activating enzyme (E1), specific for the SUMO family of ubiquitin-like proteins (Ubls). E1 enzymes are part of a conjugation cascade to attach Ub or Ubls, covalently to ...

    2. XM_059876546.1 → XP_059732529.1  SUMO-activating enzyme subunit 1 isoform X4

    3. XM_010815008.4 → XP_010813310.1  SUMO-activating enzyme subunit 1 isoform X2

      UniProtKB/TrEMBL
      A0A3Q1M9J2
      Related
      ENSBTAP00000066834.2, ENSBTAT00000067487.2
      Conserved Domains (1) summary
      cd01492
      Location:16 → 287
      Aos1_SUMO; Ubiquitin activating enzyme (E1) subunit Aos1. Aos1 is part of the heterodimeric activating enzyme (E1), specific for the SUMO family of ubiquitin-like proteins (Ubls). E1 enzymes are part of a conjugation cascade to attach Ub or Ubls, covalently to ...

    4. XM_005219193.5 → XP_005219250.1  SUMO-activating enzyme subunit 1 isoform X3

      See identical proteins and their annotated locations for XP_005219250.1

      UniProtKB/TrEMBL
      A0AAA9TS15
      Related
      ENSBTAP00000101170.1, ENSBTAT00000103824.1
      Conserved Domains (1) summary
      cd01492
      Location:16 → 169
      Aos1_SUMO; Ubiquitin activating enzyme (E1) subunit Aos1. Aos1 is part of the heterodimeric activating enzyme (E1), specific for the SUMO family of ubiquitin-like proteins (Ubls). E1 enzymes are part of a conjugation cascade to attach Ub or Ubls, covalently to ...
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A2VE14.1 GenPept UniProtKB/Swiss-Prot:A2VE14

    Gene LinkOut

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