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    CYP724A1 cytochrome P450, family 724, subfamily A, polypeptide 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831291, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CYP724A1
    Official Full Name
    cytochrome P450, family 724, subfamily A, polypeptide 1
    Primary source
    TAIR:AT5G14400
    Locus tag
    AT5G14400
    See related
    Araport:AT5G14400
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ''cytochrome P450; cytochrome P450; F18O22.190; F18O22_190; family 724; polypeptide 1; polypeptide 1''; subfamily A
    Summary
    Encodes a brassinosteroid C-22 hydroxylase.
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    Genomic context

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    See CYP724A1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    9
    Sequence:
    Chromosome: 5; NC_003076.8 (4643510..4646530)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene arabinogalactan protein 6 Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene uncharacterized protein Neighboring gene RING domain ligase2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional complementation of dwf4 mutants of Arabidopsis by overexpression of CYP724A1. Zhang R, et al. J Plant Physiol, 2012 Mar 1. PMID 22196800
    2. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Overexpression of CYP724A1 in null dwf4-102 plants functionally complements their C-22 hydroxylase deficiency.
      Title: Functional complementation of dwf4 mutants of Arabidopsis by overexpression of CYP724A1.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables steroid 22-alpha hydroxylase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within brassinosteroid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    cytochrome P450, family 724, subfamily A, polypeptide 1
    NP_196944.3
    • ''cytochrome P450, family 724, subfamily A, polypeptide 1'' (CYP724A1); FUNCTIONS IN: electron carrier activity, monooxygenase activity, iron ion binding, oxygen binding, heme binding; INVOLVED IN: oxidation reduction; LOCATED IN: cellular_component unknown; CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, E-class, group I (InterPro:IPR002401), Cytochrome P450, conserved site (InterPro:IPR017972); BEST Arabidopsis thaliana protein match is: Cytochrome P450 superfamily protein (TAIR:AT3G50660.1); Has 22938 Blast hits to 22894 proteins in 1383 species: Archae - 43; Bacteria - 3025; Metazoa - 8566; Fungi - 3762; Plants - 6637; Viruses - 3; Other Eukaryotes - 902 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      4643510..4646530
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001343334.1 → NP_001331288.1  cytochrome P450, family 724, subfamily A, polypeptide 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BDE8, A0A5S9Y4W7, A0A654G143
      Conserved Domains (1) summary
      cl41757
      Location:28 → 415
      cytochrome_P450; cytochrome P450 (CYP) superfamily

    2. NM_001343335.1 → NP_001331287.1  cytochrome P450, family 724, subfamily A, polypeptide 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UMM4, A0A1P8BDE6

    3. NM_001343336.1 → NP_001331289.1  cytochrome P450, family 724, subfamily A, polypeptide 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UMM4, A0A1P8BDE1

    4. NM_121444.4 → NP_196944.3  cytochrome P450, family 724, subfamily A, polypeptide 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196944.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654G143, F4K6S3
      Conserved Domains (1) summary
      cl12078
      Location:2 → 360
      p450; Cytochrome P450
    Nucleotide Protein
    Heading Accession and Version

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