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    ARP2 actin related protein 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 822317, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ARP2
    Official Full Name
    actin related protein 2
    Primary source
    TAIR:AT3G27000
    Locus tag
    AT3G27000
    See related
    Araport:AT3G27000
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    actin related protein 2; ACTIN RELATED PROTEIN 2; ATARP2; WRM; WURM
    Summary
    encodes a protein whose sequence is similar to actin-related proteins (ARPs) in other organisms. its transcript level is down regulated by light and is expressed in very low levels in all organs examined.
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    Genomic context

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    See ARP2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    15
    Sequence:
    Chromosome: 3; NC_003074.8 (9952479..9955982, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene membrane-anchored ubiquitin-fold protein 4 precursor Neighboring gene ENTH/VHS family protein Neighboring gene TEOSINTE BRANCHED 1, cycloidea, PCF (TCP)-domain family protein 20 Neighboring gene YELLOW STRIPE like 6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis actin-related protein 2 (AtARP2) promoter directs expression in xylem precursor cells and pollen. Klahre U, et al. Plant Mol Biol, 1999 Sep. PMID 10561069
    2. The actin-related Protein2/3 complex regulates mitochondrial-associated calcium signaling during salt stress in Arabidopsis. Zhao Y, et al. Plant Cell, 2013 Nov. PMID 24280386, Free PMC Article
    3. The ARP2/3 complex mediates guard cell actin reorganization and stomatal movement in Arabidopsis. Jiang K, et al. Plant Cell, 2012 May. PMID 22570440, Free PMC Article
    4. Mutations in actin-related proteins 2 and 3 affect cell shape development in Arabidopsis. Mathur J, et al. Plant Cell, 2003 Jul. PMID 12837952, Free PMC Article
    5. BRICK1/HSPC300 functions with SCAR and the ARP2/3 complex to regulate epidermal cell shape in Arabidopsis. Djakovic S, et al. Development, 2006 Mar. PMID 16481352

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Arp2/3 complex regulates mitochondrial-dependent Ca(2+) signaling in response to salt stress.Arp2 is required for mitochondrial distribution.
      Title: The actin-related Protein2/3 complex regulates mitochondrial-associated calcium signaling during salt stress in Arabidopsis.
    2. The work indicates that regulation of actin reassembly through ARP2/3 complex activity is crucial for stomatal regulation.
      Title: The ARP2/3 complex mediates guard cell actin reorganization and stomatal movement in Arabidopsis.
    3. The rapid growth of roots in the light requires a functional ARP2/3-SCAR complex.
      Title: SCAR mediates light-induced root elongation in Arabidopsis through photoreceptors and proteasomes.
    4. Differences among SCARs in mRNA levels and the biochemical efficiency of ARP2/3 activation may explain the functional contributions of individual genes
      Title: Arabidopsis SCARs function interchangeably to meet actin-related protein 2/3 activation thresholds during morphogenesis.
    5. BRK1 is required for accumulation of SCAR1 protein in vivo, potentially explaining the apparently essential role of BRK1 in ARP2/3 complex function
      Title: BRICK1/HSPC300 functions with SCAR and the ARP2/3 complex to regulate epidermal cell shape in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_113614.3

    Gene Ontology Provided by TAIR

    Process Evidence Code Pubs
    acts_upstream_of_or_within actin cytoskeleton organization TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within actin filament organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within actin filament-based process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within cell morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within multidimensional cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within trichome morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Arp2/3 protein complex TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    actin related protein 2
    NP_189336.1
    • actin related protein 2 (ARP2); FUNCTIONS IN: structural constituent of cytoskeleton; INVOLVED IN: in 7 processes; LOCATED IN: Arp2/3 protein complex; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: Actin/actin-like (InterPro:IPR004000); BEST Arabidopsis thaliana protein match is: Actin-like ATPase superfamily protein (TAIR:AT2G42100.1); Has 13000 Blast hits to 12789 proteins in 2576 species: Archae - 4; Bacteria - 10; Metazoa - 5530; Fungi - 3345; Plants - 1585; Viruses - 2; Other Eukaryotes - 2524 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      9952479..9955982 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113614.3 → NP_189336.1  actin related protein 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_189336.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LSD6, Q9ZSS8
      UniProtKB/TrEMBL
      A0A178V6E1, A0A5S9XGC2
      Conserved Domains (1) summary
      smart00268
      Location:4 → 387
      ACTIN; Actin
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LSD6.1

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