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    O-methyltransferase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824480, updated on 18-Sep-2024

    Summary

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    Official Full Name
    O-methyltransferase family protein
    Primary source
    TAIR:AT3G53140
    Locus tag
    AT3G53140
    See related
    Araport:AT3G53140
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    4
    Sequence:
    Chromosome: 3; NC_003074.8 (19695643..19697542)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ubiquitin-protein ligase 7 Neighboring gene GDSL-like Lipase/Acylhydrolase superfamily protein Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene Modifier of rudimentary (Mod(r)) protein Neighboring gene Cytochrome P450 superfamily protein Neighboring gene UDP-glucosyl transferase 73D1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Novel N-Methyltransferase in Arabidopsis Appears to Feed a Conserved Pathway for Nicotinate Detoxification among Land Plants and Is Associated with Lignin Biosynthesis. Li W, et al. Plant Physiol, 2017 Jul. PMID 28533213, Free PMC Article
    2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Nicotinic acid detoxification conferred by NANMT and COMT might have facilitated the retention of the Preiss-Handler pathway in land plants.[NANMT1]
      Title: A Novel N-Methyltransferase in Arabidopsis Appears to Feed a Conserved Pathway for Nicotinate Detoxification among Land Plants and Is Associated with Lignin Biosynthesis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    NM_115174.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables O-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables methyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables nicotinate N-methyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within nicotinate metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    O-methyltransferase family protein
    NP_190882.1
    • O-methyltransferase family protein; FUNCTIONS IN: methyltransferase activity, protein dimerization activity, O-methyltransferase activity; INVOLVED IN: biological_process unknown; CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Plant methyltransferase dimerisation (InterPro:IPR012967), O-methyltransferase, family 2 (InterPro:IPR001077), O-methyltransferase, COMT, eukaryota (InterPro:IPR016461); BEST Arabidopsis thaliana protein match is: O-methyltransferase 1 (TAIR:AT5G54160.1); Has 3047 Blast hits to 3042 proteins in 532 species: Archae - 0; Bacteria - 810; Metazoa - 98; Fungi - 512; Plants - 1526; Viruses - 0; Other Eukaryotes - 101 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      19695643..19697542
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115174.2 → NP_190882.1  O-methyltransferase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190882.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A178VFV7, Q9SCP7
      UniProtKB/TrEMBL
      A0A384KW10, A0A654FGY0
      Conserved Domains (2) summary
      pfam08100
      Location:27 → 82
      dimerization; dimerization domain
      cl17173
      Location:147 → 341
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SCP7.1

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