GALK Mevalonate/galactokinase family protein [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: GALK
Official Full Name: Mevalonate/galactokinase family protein
Primary source: TAIR:AT3G06580
Locus tag: AT3G06580
See related: Araport:AT3G06580
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: F5E6.9; F5E6_9; GAL1; GALACTOSE KINASE 1
Summary: Encodes a protein with galactose kinase activity. The gene was shown to complement the yeast #Ngal1 mutant defective in the galactokinase gene GAL1.
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Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

important role during phosphate deprivation through interaction with mannose-rich glycans of PAP26-S2
Title: Lectin AtGAL1 interacts with high-mannose glycoform of the purple acid phosphatase AtPAP26 secreted by phosphate-starved Arabidopsis.
An AtGALK T-DNA insertion mutant (atgalk) that (i) is AtGALK transcript deficient; (ii) displays no GALK activity in vegetative tissues; and (iii) accumulates Gal up to 6.8 mg g(-1) FW in vegetative tissues.
Title: An Arabidopsis T-DNA insertion mutant for galactokinase (AtGALK, At3g06580) hyperaccumulates free galactose and is insensitive to exogenous galactose.
galacturonic acid-1-phosphate kinase is a new member of the GHMP kinase superfamily in plants. [galacturonic acid-1-phosphate kinase]
Title: Identification of galacturonic acid-1-phosphate kinase, a new member of the GHMP kinase superfamily in plants, and comparison with galactose-1-phosphate kinase.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_111534.4

Function	Evidence Code	Pubs
enables galactokinase activity	IDA Inferred from Direct Assay more info	PubMed
enables galactokinase activity	IGI Inferred from Genetic Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within carbohydrate phosphorylation	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within carbohydrate phosphorylation	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within galactose metabolic process	IDA Inferred from Direct Assay more info	PubMed
involved_in galactose metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISM Inferred from Sequence Model more info
located_in cytosol	HDA more info	PubMed

NP_187310.1

GALK; FUNCTIONS IN: ATP binding, galactokinase activity; INVOLVED IN: galactose metabolic process, carbohydrate phosphorylation; LOCATED IN: cytoplasm; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: GHMP kinase, ATP-binding, conserved site (InterPro:IPR006203), GHMP kinase (InterPro:IPR006204), Galactokinase (InterPro:IPR000705), Mevalonate/galactokinase (InterPro:IPR006206), Galactokinase galactose-binding domain (InterPro:IPR019539), Galactokinase, conserved site (InterPro:IPR019741), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), Ribosomal protein S5 domain 2-type fold, subgroup (InterPro:IPR014721), GHMP kinase, C-terminal (InterPro:IPR013750); BEST Arabidopsis thaliana protein match is: arabinose kinase (TAIR:AT4G16130.1); Has 4768 Blast hits to 4465 proteins in 1570 species: Archae - 210; Bacteria - 3137; Metazoa - 280; Fungi - 182; Plants - 144; Viruses - 0; Other Eukaryotes - 815 (source: NCBI BLink).