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    CCD7 carotenoid cleavage dioxygenase 7 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819107, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CCD7
    Official Full Name
    carotenoid cleavage dioxygenase 7
    Primary source
    TAIR:AT2G44990
    Locus tag
    AT2G44990
    See related
    Araport:AT2G44990
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATCCD7; carotenoid cleavage dioxygenase 7; MAX3; T14P1.21
    Summary
    More Axillary Branching; carotenoid cleavage dioxygenases.
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    Genomic context

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    See CCD7 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    7
    Sequence:
    Chromosome: 2; NC_003071.7 (18558885..18561621)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene SNF2 domain-containing protein / helicase domain-containing protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene structural constituent of nuclear pore

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. On the substrate- and stereospecificity of the plant carotenoid cleavage dioxygenase 7. Bruno M, et al. FEBS Lett, 2014 May 2. PMID 24685691
    2. Vascular-specific activity of the Arabidopsis carotenoid cleavage dioxygenase 7 gene promoter. Liang YS, et al. Plant Cell Rep, 2011 Jun. PMID 21243360
    3. MAX3/CCD7 is a carotenoid cleavage dioxygenase required for the synthesis of a novel plant signaling molecule. Booker J, et al. Curr Biol, 2004 Jul 27. PMID 15268852
    4. Enzymatic study on AtCCD4 and AtCCD7 and their potential to form acyclic regulatory metabolites. Bruno M, et al. J Exp Bot, 2016 Nov. PMID 27811075, Free PMC Article
    5. Strigolactone Regulates Leaf Senescence in Concert with Ethylene in Arabidopsis. Ueda H, et al. Plant Physiol, 2015 Sep. PMID 25979917, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. enzymatic potential to form acyclic regulatory metabolites
      Title: Enzymatic study on AtCCD4 and AtCCD7 and their potential to form acyclic regulatory metabolites.
    2. The strigolactone biosynthesis genes MAX3 and MAX4 were drastically induced during dark incubation and treatment with the senescence-promoting phytohormone ethylene, suggesting that strigolactone is synthesized in the leaf during leaf senescence.
      Title: Strigolactone Regulates Leaf Senescence in Concert with Ethylene in Arabidopsis.
    3. Substrate and stereo-specificity of the Arabidopsis CCD7 enzyme.
      Title: On the substrate- and stereospecificity of the plant carotenoid cleavage dioxygenase 7.
    4. Wild-type and strigolactone mutants of A. thaliana Atccd7 and Atccd8 induced similar levels of P. ramosa seed germination, suggesting that compounds other than strigolactone function as germination stimulants for P. ramosa in other Brassicaceae spp.
      Title: Germination stimulants of Phelipanche ramosa in the rhizosphere of Brassica napus are derived from the glucosinolate pathway.
    5. The promoter activity of the 1,867-bp 5'-upstream region of AtCCD7exhibited a vascular specificity at all developmental stages throughout the transgenic Arabidopsis plants tested.
      Title: Vascular-specific activity of the Arabidopsis carotenoid cleavage dioxygenase 7 gene promoter.
    6. Results show that MAX3 and MAX4 genes were down-regulated in igi1 (Inflorescence Growth Inhibitor 1) mutants.
      Title: Over-expression of the IGI1 leading to altered shoot-branching development related to MAX pathway in Arabidopsis.
    7. Complementation analyses for HTD1 confirm that the defect in HTD1 is responsible for both high-tillering and dwarf phenotypes in the htd1 mutant; HTD1 is an ortholog of MAX3 in A. thaliana.
      Title: The rice HIGH-TILLERING DWARF1 encoding an ortholog of Arabidopsis MAX3 is required for negative regulation of the outgrowth of axillary buds.
    8. the sequential cleavages of beta-carotene by AtCCD7 and AtCCD8 may be initial steps in the synthesis of a carotenoid-derived signaling molecule necessary for the regulation lateral branching. [AtCCD7]
      Title: The biochemical characterization of two carotenoid cleavage enzymes from Arabidopsis indicates that a carotenoid-derived compound inhibits lateral branching.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 9-cis-beta-carotene 9',10'-cleavage oxygenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables 9-cis-epoxycarotenoid dioxygenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within auxin polar transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within carotene catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in carotene catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in carotene catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within secondary shoot formation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in secondary shoot formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in strigolactone biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within xanthophyll catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast stroma IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plastid IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    carotenoid cleavage dioxygenase 7
    NP_001318427.1
    • carotenoid cleavage dioxygenase 7 (CCD7); CONTAINS InterPro DOMAIN/s: Carotenoid oxygenase (InterPro:IPR004294); BEST Arabidopsis thaliana protein match is: nine-cis-epoxycarotenoid dioxygenase 6 (TAIR:AT3G24220.1); Has 211 Blast hits to 206 proteins in 62 species: Archae - 2; Bacteria - 69; Metazoa - 8; Fungi - 31; Plants - 96; Viruses - 0; Other Eukaryotes - 5 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      18558885..18561621
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130064.5 → NP_182026.5  carotenoid cleavage dioxygenase 7 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VU61, A0A1P8B119, A0A5S9X7E2

    2. NM_001337112.1 → NP_001324720.1  carotenoid cleavage dioxygenase 7 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VU61, A0A1P8B107, A0A5S9X7E2

    3. NM_001337111.1 → NP_001318427.1  carotenoid cleavage dioxygenase 7 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4IV47, Q0WMG3, Q7XJM2
      UniProtKB/TrEMBL
      A0A178VU61, A0A5S9X7E2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7XJM2.1

    Gene LinkOut

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