U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Aldolase superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817221, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Full Name
    Aldolase superfamily protein
    Primary source
    TAIR:AT2G26800
    Locus tag
    AT2G26800
    See related
    Araport:AT2G26800
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Summary
    Mutant has increased seed ile, leu and val as well as his and arg.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    chromosome: 2
    Exon count:
    9
    Sequence:
    Chromosome: 2; NC_003071.7 (11429019..11432797, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ARM repeat superfamily protein Neighboring gene ncRNA Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene Putative methyltransferase family protein Neighboring gene phloem protein 2-A3

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Chloroplast 2010: a database for large-scale phenotypic screening of Arabidopsis mutants. Lu Y, et al. Plant Physiol, 2011 Apr. PMID 21224340, Free PMC Article
    2. Lipoic acid-dependent oxidative catabolism of alpha-keto acids in mitochondria provides evidence for branched-chain amino acid catabolism in Arabidopsis. Taylor NL, et al. Plant Physiol, 2004 Feb. PMID 14764908, Free PMC Article
    3. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234
    4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    5. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_001336085.1
    NM_001336086.1
    NM_128237.3
    NM_179756.4
    NM_179757.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables hydroxymethylglutaryl-CoA lyase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables hydroxymethylglutaryl-CoA lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydroxymethylglutaryl-CoA lyase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables metal ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Aldolase superfamily protein
    NP_565629.1
    • Aldolase superfamily protein; FUNCTIONS IN: hydroxymethylglutaryl-CoA lyase activity, catalytic activity; INVOLVED IN: leucine metabolic process, metabolic process; LOCATED IN: mitochondrion; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), Pyruvate carboxyltransferase (InterPro:IPR000891); BEST Arabidopsis thaliana protein match is: 2-isopropylmalate synthase 2 (TAIR:AT5G23020.1); Has 10793 Blast hits to 10779 proteins in 2209 species: Archae - 423; Bacteria - 7034; Metazoa - 235; Fungi - 307; Plants - 196; Viruses - 0; Other Eukaryotes - 2598 (source: NCBI BLink).
    NP_850087.1
    • Aldolase superfamily protein; FUNCTIONS IN: hydroxymethylglutaryl-CoA lyase activity, catalytic activity; INVOLVED IN: leucine metabolic process, metabolic process; LOCATED IN: mitochondrion; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), Pyruvate carboxyltransferase (InterPro:IPR000891); BEST Arabidopsis thaliana protein match is: 2-isopropylmalate synthase 2 (TAIR:AT5G23020.1); Has 10820 Blast hits to 10806 proteins in 2215 species: Archae - 426; Bacteria - 7058; Metazoa - 235; Fungi - 307; Plants - 196; Viruses - 0; Other Eukaryotes - 2598 (source: NCBI BLink).
    NP_850088.1
    • Aldolase superfamily protein; FUNCTIONS IN: hydroxymethylglutaryl-CoA lyase activity, catalytic activity; INVOLVED IN: leucine metabolic process, metabolic process; LOCATED IN: mitochondrion; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), Pyruvate carboxyltransferase (InterPro:IPR000891); Has 2834 Blast hits to 2828 proteins in 876 species: Archae - 8; Bacteria - 1833; Metazoa - 220; Fungi - 120; Plants - 70; Viruses - 0; Other Eukaryotes - 583 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      11429019..11432797 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_179756.4 → NP_850087.1  Aldolase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850087.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2ECP1
      Conserved Domains (2) summary
      PLN02746
      Location:87 → 433
      PLN02746; hydroxymethylglutaryl-CoA lyase
      pfam00682
      Location:133 → 406
      HMGL-like; HMGL-like

    2. NM_128237.3 → NP_565629.1  Aldolase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565629.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O81027, Q8L7K2, Q9FPE2
      UniProtKB/TrEMBL
      A0A5S9X1Q0
      Conserved Domains (2) summary
      PLN02746
      Location:122 → 468
      PLN02746; hydroxymethylglutaryl-CoA lyase
      pfam00682
      Location:168 → 441
      HMGL-like; HMGL-like

    3. NM_001336085.1 → NP_001324446.1  Aldolase superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O81027, Q8L7K2, Q9FPE2
      UniProtKB/TrEMBL
      A0A5S9X1Q0

    4. NM_001336086.1 → NP_001324445.1  Aldolase superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B070, A0A7G2ECP1

    5. NM_179757.2 → NP_850088.1  Aldolase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850088.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4IVK2
      Conserved Domains (1) summary
      PLN02746
      Location:122 → 350
      PLN02746; hydroxymethylglutaryl-CoA lyase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O81027.2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.