gcy-34 Soluble guanylate cyclase gcy-34 [Caenorhabditis elegans] - Gene

Summary

Official Symbol: gcy-34
Official Full Name: Soluble guanylate cyclase gcy-34
Primary source: WormBase:WBGene00001554
Locus tag: CELE_M04G12.3
See related: AllianceGenome:WB:WBGene00001554
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable guanylate cyclase activity. Involved in chemosensory behavior and sensory perception of bitter taste. Predicted to be located in cytoplasm. Predicted to be part of guanylate cyclase complex, soluble. Is expressed in AQR; PQR; URXL; and URXR. Orthologous to several human genes including GUCY1B2 (guanylate cyclase 1 soluble subunit beta 2 (pseudogene)). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

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Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables guanylate cyclase activity	IBA Inferred from Biological aspect of Ancestor more info
enables guanylate cyclase activity	IEA Inferred from Electronic Annotation more info
enables heme binding	IEA Inferred from Electronic Annotation more info
enables lyase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in cGMP biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in cGMP-mediated signaling	IBA Inferred from Biological aspect of Ancestor more info
involved_in chemosensory behavior	IGI Inferred from Genetic Interaction more info	PubMed
involved_in chemosensory behavior	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cyclic nucleotide biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in intracellular signal transduction	IEA Inferred from Electronic Annotation more info
involved_in response to oxygen levels	IBA Inferred from Biological aspect of Ancestor more info
involved_in sensory perception of bitter taste	IGI Inferred from Genetic Interaction more info	PubMed
involved_in sensory perception of bitter taste	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
part_of guanylate cyclase complex, soluble	IBA Inferred from Biological aspect of Ancestor more info

NP_506319.1

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The following sections contain reference sequences that belong to a specific genome build. Explain