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    tag-273 LIM zinc-binding domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 178388, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tag-273
    Official Full Name
    LIM zinc-binding domain-containing protein
    Primary source
    WormBase:WBGene00013289
    Locus tag
    CELE_Y57G11A.1
    See related
    AllianceGenome:WB:WBGene00013289
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable actin filament binding activity. Predicted to be involved in actin filament bundle assembly. Predicted to be active in actin cytoskeleton and plasma membrane. Orthologous to human LIMA1 (LIM domain and actin binding 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See tag-273 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    17
    Sequence:
    Chromosome: IV; NC_003282.8 (14487087..14505166, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of a LIM domain-containing gene in the Cyathostominae. Matthews JB, et al. Vet Parasitol, 2008 Jun 14. PMID 18406533
    2. Genome-wide functional analysis of CREB/long-term memory-dependent transcription reveals distinct basal and memory gene expression programs. Lakhina V, et al. Neuron, 2015 Jan 21. PMID 25611510, Free PMC Article
    3. Identification of cross-linked peptides from complex samples. Yang B, et al. Nat Methods, 2012 Sep. PMID 22772728
    4. The mechanoreceptor DEG-1 regulates cold tolerance in Caenorhabditis elegans. Takagaki N, et al. EMBO Rep, 2020 Mar 4. PMID 32009302, Free PMC Article
    5. The Caenorhabditis elegans RDE-10/RDE-11 complex regulates RNAi by promoting secondary siRNA amplification. Zhang C, et al. Curr Biol, 2012 May 22. PMID 22542102, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in actin filament bundle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    LIM zinc-binding domain-containing protein
    NP_001023516.1
    • Confirmed by transcript evidence
    NP_001023517.2
    • Confirmed by transcript evidence
    NP_001255812.1
    • Confirmed by transcript evidence
    NP_001255813.1
    • Partially confirmed by transcript evidence
    NP_001294000.1
    • Confirmed by transcript evidence
    NP_001294001.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      14487087..14505166 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001028345.6 → NP_001023516.1  LIM zinc-binding domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001023516.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O18221
      Conserved Domains (2) summary
      PTZ00121
      Location:11 → 469
      PTZ00121; MAEBL; Provisional
      cd09358
      Location:508 → 562
      LIM_Mical_like; The LIM domain of Mical (molecule interacting with CasL) like family

    2. NM_001307072.3 → NP_001294001.1  LIM zinc-binding domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294001.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A061AE99
      Conserved Domains (3) summary
      PTZ00121
      Location:263 → 754
      PTZ00121; MAEBL; Provisional
      cd09358
      Location:793 → 847
      LIM_Mical_like; The LIM domain of Mical (molecule interacting with CasL) like family
      cl02475
      Location:192 → 244
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    3. NM_001307071.3 → NP_001294000.1  LIM zinc-binding domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294000.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A061AD47
      Conserved Domains (3) summary
      PTZ00121
      Location:271 → 762
      PTZ00121; MAEBL; Provisional
      cd09358
      Location:801 → 855
      LIM_Mical_like; The LIM domain of Mical (molecule interacting with CasL) like family
      cl02475
      Location:200 → 252
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    4. NM_001268883.3 → NP_001255812.1  LIM zinc-binding domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255812.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L2L0
      Conserved Domains (1) summary
      cl02475
      Location:39 → 93
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    5. NM_001028346.5 → NP_001023517.2  LIM zinc-binding domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001023517.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86CZ7
      Conserved Domains (2) summary
      PTZ00121
      Location:263 → 754
      PTZ00121; MAEBL; Provisional
      cd09358
      Location:192 → 244
      LIM_Mical_like; The LIM domain of Mical (molecule interacting with CasL) like family

    6. NM_001268884.3 → NP_001255813.1  LIM zinc-binding domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255813.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L2L1
      Conserved Domains (2) summary
      PTZ00121
      Location:539 → 818
      PTZ00121; MAEBL; Provisional
      cd09358
      Location:192 → 244
      LIM_Mical_like; The LIM domain of Mical (molecule interacting with CasL) like family
    Nucleotide Protein
    Heading Accession and Version

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