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    lron-12 eLRR (extracellular Leucine-Rich Repeat) ONly [ Caenorhabditis elegans ]

    Gene ID: 190700, updated on 9-Dec-2024

    Summary

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    Official Symbol
    lron-12
    Official Full Name
    eLRR (extracellular Leucine-Rich Repeat) ONly
    Primary source
    WormBase:WBGene00013542
    Locus tag
    CELE_Y75B8A.5
    See related
    AllianceGenome:WB:WBGene00013542
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable potassium channel activator activity; transmembrane transporter binding activity; and voltage-gated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in membrane. Predicted to be part of voltage-gated potassium channel complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See lron-12 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    6
    Sequence:
    Chromosome: III; NC_003281.10 (12114565..12118481, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Carboxylesterase type B domain-containing protein Neighboring gene Lon protease homolog 2, peroxisomal Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene CXXC-type domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An integrated strategy to study muscle development and myofilament structure in Caenorhabditis elegans. Meissner B, et al. PLoS Genet, 2009 Jun. PMID 19557190, Free PMC Article
    2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in potassium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    eLRR (extracellular Leucine-Rich Repeat) ONly
    NP_001366666.1
    • Product from WormBase gene class lron;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      12114565..12118481 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001379945.3 → NP_001366666.1  eLRR (extracellular Leucine-Rich Repeat) ONly [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XW74
      Conserved Domains (3) summary
      sd00033
      Location:45 → 67
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13306
      Location:66 → 184
      LRR_5; Leucine rich repeats (6 copies)
      pfam13855
      Location:221 → 267
      LRR_8; Leucine rich repeat
    Nucleotide Protein
    Heading Accession and Version

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