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    ugt-16 UDP-glucuronosyltransferase [ Caenorhabditis elegans ]

    Gene ID: 191171, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ugt-16
    Official Full Name
    UDP-glucuronosyltransferase
    Primary source
    WormBase:WBGene00013901
    Locus tag
    CELE_ZC443.6
    See related
    AllianceGenome:WB:WBGene00013901
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is expressed in intestine and pharynx. Orthologous to human UGT3A1 (UDP glycosyltransferase family 3 member A1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ugt-16 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    7
    Sequence:
    Chromosome: V; NC_003283.11 (12825024..12827442)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene DUF659 domain-containing protein Neighboring gene UDP-glucuronosyltransferase Neighboring gene UDP-glucuronosyltransferase Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Polyunsaturated fatty acids and p38-MAPK link metabolic reprogramming to cytoprotective gene expression during dietary restriction. Chamoli M, et al. Nat Commun, 2020 Sep 25. PMID 32978396, Free PMC Article
    2. Using RNA interference to identify specific modifiers of a temperature-sensitive, embryonic-lethal mutation in the Caenorhabditis elegans ubiquitin-like Nedd8 protein modification pathway E1-activating gene rfl-1. Dorfman M, et al. Genetics, 2009 Aug. PMID 19528325, Free PMC Article
    3. UDP-glycosyltransferase family in Haemonchus contortus: Phylogenetic analysis, constitutive expression, sex-differences and resistance-related differences. Matoušková P, et al. Int J Parasitol Drugs Drug Resist, 2018 Dec. PMID 30293057, Free PMC Article
    4. Differential expression of genes in C. elegans reveals transcriptional responses to indirect-acting xenobiotic compounds and insensitivity to 2,3,7,8-tetrachlorodibenzodioxin. Karengera A, et al. Ecotoxicol Environ Saf, 2022 Mar 15. PMID 35219257
    5. Transcriptome analyses describe the consequences of persistent HIF-1 over-activation in Caenorhabditis elegans. Feng D, et al. PLoS One, 2024. PMID 38517909, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables UDP-glycosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables UDP-glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glucuronosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    UDP-glucuronosyltransferase
    NP_506210.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      12825024..12827442
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073809.7 → NP_506210.1  UDP-glucuronosyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506210.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EGK7
      Conserved Domains (3) summary
      PHA03392
      Location:246 → 503
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      pfam00201
      Location:19 → 532
      UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase
      pfam07219
      Location:483 → 531
      HemY_N; HemY protein N-terminus
    Nucleotide Protein
    Heading Accession and Version

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