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    ins-23 putative insulin-like peptide alpha-type 3 [ Caenorhabditis elegans ]

    Gene ID: 191691, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ins-23
    Official Full Name
    putative insulin-like peptide alpha-type 3
    Primary source
    WormBase:WBGene00002106
    Locus tag
    CELE_M04D8.3
    See related
    AllianceGenome:WB:WBGene00002106
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Is expressed in gonad; neurons; non-striated muscle; pharynx; and somatic nervous system. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ins-23 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    2
    Sequence:
    Chromosome: III; NC_003281.10 (10028247..10028697)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene putative insulin-like peptide alpha-type 1 Neighboring gene putative insulin-like peptide alpha-type 2 Neighboring gene RDD domain-containing protein Neighboring gene Serpentine Receptor, class H

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comparison of physiological functions of antagonistic insulin-like peptides, INS-23 and INS-18, in Caenorhabditis elegans. Matsunaga Y, et al. Biosci Biotechnol Biochem, 2018 Jan. PMID 29303423
    2. Males shorten the life span of C. elegans hermaphrodites via secreted compounds. Maures TJ, et al. Science, 2014 Jan 31. PMID 24292626, Free PMC Article
    3. daf-28 encodes a C. elegans insulin superfamily member that is regulated by environmental cues and acts in the DAF-2 signaling pathway. Li W, et al. Genes Dev, 2003 Apr 1. PMID 12654727, Free PMC Article
    4. Transcriptional profile of aging in C. elegans. Lund J, et al. Curr Biol, 2002 Sep 17. PMID 12372248
    5. Insulin worms its way into the spotlight. Nelson DW, et al. Genes Dev, 2003 Apr 1. PMID 12670864

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative insulin-like peptide alpha-type 3
    NP_499224.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      10028247..10028697
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066823.2 → NP_499224.1  putative insulin-like peptide alpha-type 3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499224.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q21506
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q21506.1

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