U.S. flag

An official website of the United States government

Links from GEO Profiles

    • Showing Current items.

    let-765 Protein strawberry notch homolog [ Caenorhabditis elegans ]

    Gene ID: 175934, updated on 9-Dec-2024

    Summary

    Official Symbol
    let-765
    Official Full Name
    Protein strawberry notch homolog
    Primary source
    WormBase:WBGene00002889
    Locus tag
    CELE_F20H11.2
    See related
    AllianceGenome:WB:WBGene00002889
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable chromatin DNA binding activity and histone binding activity. Involved in several processes, including nematode male tail tip morphogenesis; positive regulation of Ras protein signal transduction; and vulval cell fate specification. Located in nucleus. Is expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P5.p hermaphrodite; P6.p hermaphrodite; and P7.p hermaphrodite. Orthologous to several human genes including SBNO1 (strawberry notch homolog 1). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See let-765 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    15
    Sequence:
    Chromosome: III; NC_003281.10 (6592525..6601173, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene D-aspartate oxidase 3 Neighboring gene Differentially expressed in FDCP 8 homolog Neighboring gene ncRNA Neighboring gene Malate dehydrogenase, mitochondrial Neighboring gene Protein-tyrosine phosphatase

    Bibliography

    Interactions

    General gene information

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables chromatin DNA binding  
    enables histone binding  
    Component Evidence Code Pubs
    is_active_in nucleus  
    located_in nucleus PubMed 
    located_in nucleus  

    General protein information

    Preferred Names
    Protein strawberry notch homolog
    NP_498455.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      6592525..6601173 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066054.6 → NP_498455.2  Protein strawberry notch homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498455.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D5LYH1, O01737
      Conserved Domains (2) summary
      pfam13871
      Location:1352 → 1630
      Helicase_C_4; C-terminal domain on Strawberry notch homolog
      pfam13872
      Location:632 → 936
      AAA_34; P-loop containing NTP hydrolase pore-1
    External link. Please review our privacy policy.