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    srx-97 7TM GPCR serpentine receptor class x (Srx) domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 184672, updated on 9-Dec-2024

    Summary

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    Official Symbol
    srx-97
    Official Full Name
    7TM GPCR serpentine receptor class x (Srx) domain-containing protein
    Primary source
    WormBase:WBGene00005988
    Locus tag
    CELE_F19B10.7
    See related
    AllianceGenome:WB:WBGene00005988
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable G protein-coupled olfactory receptor activity. Involved in olfactory behavior. Located in non-motile cilium. Is expressed in ASHL; ASHR; PHBL; and PHBR. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See srx-97 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    9
    Sequence:
    Chromosome: II; NC_003280.10 (3667152..3669415, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Organ specific protein Neighboring gene ATPase Neighboring gene 7TM GPCR serpentine receptor class x (Srx) domain-containing protein Neighboring gene T-box transcription factor 18 Neighboring gene HOOK domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Increased dopaminergic neurotransmission results in ethanol dependent sedative behaviors in Caenorhabditis elegans. Pandey P, et al. PLoS Genet, 2021 Feb. PMID 33524034, Free PMC Article
    2. The G-Protein-Coupled Receptor SRX-97 Is Required for Concentration-Dependent Sensing of Benzaldehyde in Caenorhabditis elegans. Kadam NY, et al. eNeuro, 2021 Jan-Feb. PMID 33397797, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables G protein-coupled olfactory receptor activity IC
    Inferred by Curator
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in detection of chemical stimulus involved in sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in olfactory behavior IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in non-motile cilium IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    7TM GPCR serpentine receptor class x (Srx) domain-containing protein
    NP_494609.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      3667152..3669415 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_062208.4 → NP_494609.1  7TM GPCR serpentine receptor class x (Srx) domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_494609.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O02071
      Conserved Domains (1) summary
      pfam10328
      Location:35 → 291
      7TM_GPCR_Srx; Serpentine type 7TM GPCR chemoreceptor Srx
    Nucleotide Protein
    Heading Accession and Version

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