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    cnc-4 CaeNaCin (Caenorhabditis bacteriocin) [ Caenorhabditis elegans ]

    Gene ID: 178635, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cnc-4
    Official Full Name
    CaeNaCin (Caenorhabditis bacteriocin)
    Primary source
    WormBase:WBGene00000558
    Locus tag
    CELE_R09B5.9
    See related
    AllianceGenome:WB:WBGene00000558
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in defense response to fungus and innate immune response. Predicted to be located in membrane. Is expressed in hypodermis and intestine. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See cnc-4 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    2
    Sequence:
    Chromosome: V; NC_003283.11 (1447195..1447707)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene CaeNaCin (Caenorhabditis bacteriocin) Neighboring gene CaeNaCin (Caenorhabditis bacteriocin) Neighboring gene CaeNaCin (Caenorhabditis bacteriocin) Neighboring gene CaeNaCin (Caenorhabditis bacteriocin)

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A nematode-derived, mitochondrial stress signaling-regulated peptide exhibits broad antibacterial activity. Sapkota M, et al. Biol Open, 2021 May 15. PMID 34184732, Free PMC Article
    2. Evaluation of Caenorhabditis elegans as a host model for Paracoccidioides brasiliensis and Paracoccidioides lutzii. Scorzoni L, et al. Pathog Dis, 2018 Feb 1. PMID 29361158
    3. Assessment of nanopolystyrene toxicity under fungal infection condition in Caenorhabditis elegans. Li D, et al. Ecotoxicol Environ Saf, 2020 Jul 1. PMID 32302863
    4. Candida albicans infection of Caenorhabditis elegans induces antifungal immune defenses. Pukkila-Worley R, et al. PLoS Pathog, 2011 Jun. PMID 21731485, Free PMC Article
    5. ifas-1 is upregulated by fungal infection in a GPA-12 and STA-2-independent manner in the Caenorhabditis elegans epidermis. Omi S, et al. MicroPubl Biol, 2021 May 25. PMID 34056565, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in defense response to fungus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in innate immune response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    CaeNaCin (Caenorhabditis bacteriocin)
    NP_503416.1
    • Product from WormBase gene class cnc;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      1447195..1447707
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_071015.7 → NP_503416.1  CaeNaCin (Caenorhabditis bacteriocin) [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_503416.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O44613
    Nucleotide Protein
    Heading Accession and Version

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