swd-2.2 WD_REPEATS_REGION domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: swd-2.2
Official Full Name: WD_REPEATS_REGION domain-containing protein
Primary source: WormBase:WBGene00016374
Locus tag: CELE_C33H5.7
See related: AllianceGenome:WB:WBGene00016374
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable chromatin binding activity. Involved in programmed cell death. Predicted to be located in nucleus. Predicted to be part of Set1C/COMPASS complex. Is expressed in linker cell. Orthologous to human WDR82 (WD repeat domain 82). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See swd-2.2 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 6

Sequence:: Chromosome: IV; NC_003282.8 (7774411..7776038)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C46A5.9 (e-PCR)
- UniSTS:308787

C33H5.7 (e-PCR)
- UniSTS:308702

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables chromatin binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in DNA-templated transcription termination	IEA Inferred from Electronic Annotation more info
involved_in programmed cell death	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of Set1C/COMPASS complex	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: WD_REPEATS_REGION domain-containing protein

NP_501280.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

7774411..7776038

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_068879.7 → NP_501280.1 WD_REPEATS_REGION domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_501280.1

Status: REVIEWED

UniProtKB/TrEMBL

Q18403

Conserved Domains (2) summary

sd00039
Location:72 → 110

7WD40; WD40 repeat [structural motif]

cl29593
Location:26 → 313

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...