map-1 C6H2-type domain-containing protein;Methionine aminopeptidase [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: map-1
Official Full Name: C6H2-type domain-containing protein;Methionine aminopeptidase
Primary source: WormBase:WBGene00003129
Locus tag: CELE_Y37E11AL.7
See related: AllianceGenome:WB:WBGene00003129
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable metalloaminopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in cytosolic ribosome. Predicted to be active in cytosol. Orthologous to human METAP1 (methionyl aminopeptidase 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See map-1 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 7

Sequence:: Chromosome: IV; NC_003282.8 (3683537..3686865, complement)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables aminopeptidase activity	IEA Inferred from Electronic Annotation more info
enables initiator methionyl aminopeptidase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables metalloaminopeptidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables metalloaminopeptidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in proteolysis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosolic ribosome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: C6H2-type domain-containing protein;Methionine aminopeptidase

NP_001368273.1

Confirmed by transcript evidence

NP_001417869.1

Confirmed by transcript evidence

NP_500396.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

3683537..3686865 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_067995.4 → NP_500396.2 Methionine aminopeptidase [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_500396.2

Status: REVIEWED

UniProtKB/TrEMBL

Q965Y1

Conserved Domains (3) summary

PLN03158
Location:9 → 356

PLN03158; methionine aminopeptidase; Provisional

cd01086
Location:118 → 355

MetAP1; Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.

pfam15801
Location:11 → 50

zf-C6H2; zf-MYND-like zinc finger, mRNA-binding
NM_001380156.1 → NP_001368273.1 Methionine aminopeptidase [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

U4PBI7

Conserved Domains (1) summary

PLN03158
Location:1 → 57

PLN03158; methionine aminopeptidase; Provisional
NM_001430921.1 → NP_001417869.1 C6H2-type domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

U4PER3