U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    slmp-1 FHA domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 187433, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    slmp-1
    Official Full Name
    FHA domain-containing protein
    Primary source
    WormBase:WBGene00019766
    Locus tag
    CELE_M4.1
    See related
    AllianceGenome:WB:WBGene00019766
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in negative regulation of hippo signaling. Orthologous to several human genes including SLMAP (sarcolemma associated protein). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See slmp-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    8
    Sequence:
    Chromosome: IV; NC_003282.8 (3213760..3220303)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene Phosphorylase b kinase regulatory subunit Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. STRIPAK regulation of katanin microtubule severing in the Caenorhabditis elegans embryo. Lu T, et al. Genetics, 2022 May 5. PMID 35298637, Free PMC Article
    2. CCM-3 Promotes C. elegans Germline Development by Regulating Vesicle Trafficking Cytokinesis and Polarity. Pal S, et al. Curr Biol, 2017 Mar 20. PMID 28285997
    3. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
    4. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
    5. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in negative regulation of hippo signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    FHA domain-containing protein
    NP_001294341.1
    • Confirmed by transcript evidence
    NP_001294342.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      3213760..3220303
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001307413.4 → NP_001294342.1  FHA domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294342.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PEB6
      Conserved Domains (2) summary
      COG1196
      Location:162 → 361
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00060
      Location:11 → 113
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...

    2. NM_001307412.2 → NP_001294341.1  FHA domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294341.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PR75
      Conserved Domains (2) summary
      COG1196
      Location:97 → 359
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00060
      Location:11 → 113
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools