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    Y73B6BL.14 DNA ligase ATP-dependent N-terminal domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 190650, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y73B6BL.14
    Official Full Name
    DNA ligase ATP-dependent N-terminal domain-containing protein
    Primary source
    WormBase:WBGene00022237
    Locus tag
    CELE_Y73B6BL.14
    See related
    AllianceGenome:WB:WBGene00022237
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable ATP binding activity; DNA binding activity; and DNA ligase (ATP) activity. Predicted to be involved in DNA recombination and DNA repair. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 20 and pancreatic cancer. Orthologous to human LIG3 (DNA ligase 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y73B6BL.14 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    4
    Sequence:
    Chromosome: IV; NC_003282.8 (6342471..6342976, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Macrophage migration inhibitory factor Neighboring gene PNPLA domain-containing protein Neighboring gene RRM domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Biogenesis of lysosome-related organelles complex 1 subunit 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA ligase (ATP) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA recombination IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DNA ligase ATP-dependent N-terminal domain-containing protein
    NP_500970.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      6342471..6342976 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068569.5 → NP_500970.2  DNA ligase ATP-dependent N-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500970.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9GUG2
      Conserved Domains (1) summary
      pfam04675
      Location:14 → 88
      DNA_ligase_A_N; DNA ligase N-terminus
    Nucleotide Protein
    Heading Accession and Version

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