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    aatf-1 Protein BFR2 [ Caenorhabditis elegans ]

    Gene ID: 171723, updated on 9-Dec-2024

    Summary

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    Official Symbol
    aatf-1
    Official Full Name
    Protein BFR2
    Primary source
    WormBase:WBGene00022269
    Locus tag
    CELE_Y73E7A.2
    See related
    AllianceGenome:WB:WBGene00022269
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in nucleus. Predicted to be active in nucleolus. Orthologous to human AATF (apoptosis antagonizing transcription factor). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See aatf-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003279.8 (1601838..1607219)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Putative complexin-1 Neighboring gene pseudo Neighboring gene Bladder cancer-associated protein Neighboring gene WD and tetratricopeptide repeats protein 1;WD_REPEATS_REGION domain-containing protein Neighboring gene Beta-1,4-N-acetylgalactosaminyltransferase bre-4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Coordinate Regulation of Ribosome and tRNA Biogenesis Controls Hypoxic Injury and Translation. Itani OA, et al. Curr Biol, 2021 Jan 11. PMID 33157031, Free PMC Article
    2. The relationship between intraflagellar transport and upstream protein trafficking pathways and macrocyclic lactone resistance in Caenorhabditis elegans. Brinzer RA, et al. G3 (Bethesda), 2024 Mar 6. PMID 38227795, Free PMC Article
    3. Defect-buffering cellular plasticity increases robustness of metazoan embryogenesis. Xiao L, et al. Cell Syst, 2022 Aug 17. PMID 35882226
    4. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
    5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Protein BFR2
    NP_490870.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      1601838..1607219
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058469.8 → NP_490870.2  Protein BFR2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_490870.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9GUM5
      Conserved Domains (2) summary
      pfam08164
      Location:375 → 462
      TRAUB; Apoptosis-antagonizing transcription factor, C-terminal
      pfam13339
      Location:142 → 303
      AATF-Che1; Apoptosis antagonizing transcription factor
    Nucleotide Protein
    Heading Accession and Version

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