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    rga-4 Rho-GAP domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 178629, updated on 9-Dec-2024

    Summary

    Official Symbol
    rga-4
    Official Full Name
    Rho-GAP domain-containing protein
    Primary source
    WormBase:WBGene00022286
    Locus tag
    CELE_Y75B7AL.4
    See related
    AllianceGenome:WB:WBGene00022286
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables GTPase activator activity. Involved in asymmetric protein localization involved in cell fate determination; cortical actin cytoskeleton organization; and regulation of actin filament-based process. Is expressed in embryonic cell and germ line. Orthologous to human ARHGAP11A (Rho GTPase activating protein 11A). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See rga-4 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    9
    Sequence:
    Chromosome: V; NC_003283.11 (1373120..1383256, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene C2 domain-containing protein Neighboring gene ncRNA Neighboring gene DUF148 domain-containing protein Neighboring gene C2 domain-containing protein

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables GTPase activator activity  
    enables GTPase activator activity PubMed 
    enables GTPase activator activity PubMed 

    General protein information

    Preferred Names
    Rho-GAP domain-containing protein
    NP_001041201.1
    • Confirmed by transcript evidence
    NP_001041202.1
    • Confirmed by transcript evidence
    NP_001300288.1
    • Partially confirmed by transcript evidence
    NP_001300289.1
    • Confirmed by transcript evidence
    NP_001300290.1
    • Confirmed by transcript evidence
    NP_001300291.1
    • Confirmed by transcript evidence
    NP_001300292.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      1373120..1383256 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001047736.4NP_001041201.1  Rho-GAP domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001041201.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q965S4
      Conserved Domains (1) summary
      smart00324
      Location:63230
      RhoGAP; GTPase-activator protein for Rho-like GTPases
    2. NM_001313359.5NP_001300288.1  Rho-GAP domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AW57
      Conserved Domains (1) summary
      smart00324
      Location:63230
      RhoGAP; GTPase-activator protein for Rho-like GTPases
    3. NM_001047737.3NP_001041202.1  Rho-GAP domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001041202.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KZS7
      Conserved Domains (1) summary
      smart00324
      Location:63235
      RhoGAP; GTPase-activator protein for Rho-like GTPases
    4. NM_001313361.3NP_001300290.1  Rho-GAP domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AT49
      Conserved Domains (1) summary
      smart00324
      Location:1150
      RhoGAP; GTPase-activator protein for Rho-like GTPases
    5. NM_001313360.3NP_001300289.1  Rho-GAP domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AYE4
      Conserved Domains (1) summary
      smart00324
      Location:1150
      RhoGAP; GTPase-activator protein for Rho-like GTPases
    6. NM_001313363.3NP_001300292.1  Rho-GAP domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3ASJ8
    7. NM_001313362.3NP_001300291.1  Rho-GAP domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AVE9
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