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    F15E6.6 Xanthine dehydrogenase [ Caenorhabditis elegans ]

    Gene ID: 177192, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F15E6.6
    Official Full Name
    Xanthine dehydrogenase
    Primary source
    WormBase:WBGene00017487
    Locus tag
    CELE_F15E6.6
    See related
    AllianceGenome:WB:WBGene00017487
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable oxidoreductase activity. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F15E6.6 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    16
    Sequence:
    Chromosome: IV; NC_003282.8 (4278825..4284120, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Nuclear Hormone Receptor family Neighboring gene ncRNA Neighboring gene Serpentine Receptor, class T;Serpentine receptor class gamma

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. C30F12.4 influences oogenesis, fat metabolism, and lifespan in C. elegans. Wang L, et al. Protein Cell, 2016 Oct. PMID 27638466, Free PMC Article
    2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables 2 iron, 2 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables iron-sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Xanthine dehydrogenase
    NP_500531.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      4278825..4284120 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068130.6 → NP_500531.2  Xanthine dehydrogenase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500531.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O61198
      Conserved Domains (6) summary
      PLN02906
      Location:23 → 1253
      PLN02906; xanthine dehydrogenase
      cd00207
      Location:6 → 77
      fer2; 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis ...
      pfam01315
      Location:528 → 640
      Ald_Xan_dh_C; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
      pfam01799
      Location:87 → 158
      Fer2_2; [2Fe-2S] binding domain
      pfam02738
      Location:678 → 1180
      Ald_Xan_dh_C2; Molybdopterin-binding domain of aldehyde dehydrogenase
      cl19922
      Location:279 → 382
      FAD_binding_4; FAD binding domain
    Nucleotide Protein
    Heading Accession and Version

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