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    Luc7l LUC7-like [ Rattus norvegicus (Norway rat) ]

    Gene ID: 360503, updated on 3-Dec-2024

    Summary

    Symbol
    Luc7lprovided by RGD
    Full Name
    LUC7-likeprovided by RGD
    Primary source
    RGD:1307542
    See related
    EnsemblRapid:ENSRNOG00000020488 AllianceGenome:RGD:1307542
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Luc7l1
    Summary
    Predicted to enable RS domain binding activity; identical protein binding activity; and mRNA binding activity. Predicted to be involved in mRNA splice site recognition. Predicted to act upstream of or within negative regulation of striated muscle tissue development. Predicted to be part of U1 snRNP and U2-type prespliceosome. Orthologous to human LUC7L (LUC7 like). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Adrenal (RPKM 112.1), Thymus (RPKM 102.7) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Luc7l in Genome Data Viewer
    Location:
    10q12
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (15777837..15811586)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (15273340..15307131)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (15538878..15572651)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 234, member A Neighboring gene uncharacterized LOC108352066 Neighboring gene small nucleolar RNA SNORA44 Neighboring gene small nucleolar RNA U13 Neighboring gene hemoglobin alpha, adult chain 3 Neighboring gene hemoglobin, theta 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RS domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in mRNA splice site recognition IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within negative regulation of striated muscle tissue development ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of U1 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of U2-type prespliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    putative RNA-binding protein Luc7-like 1
    Names
    LUC7-like 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001399674.1NP_001386603.1  putative RNA-binding protein Luc7-like 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A0A8I6G7J5, A6HDA0, G3V9R0, Q5FVI7
      Related
      ENSRNOP00000087424.2, ENSRNOT00000109984.2
    2. NM_001399675.1NP_001386604.1  putative RNA-binding protein Luc7-like 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      A0A0G2QBZ8, A0A8I6A458, A6HDA1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      15777837..15811586
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039086288.2XP_038942216.1  putative RNA-binding protein Luc7-like 1 isoform X1

      UniProtKB/TrEMBL
      A0A0G2QBZ8
      Conserved Domains (1) summary
      pfam03194
      Location:5242
      LUC7; LUC7 N_terminus
    2. XM_017597369.3XP_017452858.1  putative RNA-binding protein Luc7-like 1 isoform X2

      UniProtKB/TrEMBL
      A0A0G2QBZ8
      Related
      ENSRNOP00000081119.1, ENSRNOT00000118201.2
      Conserved Domains (1) summary
      pfam03194
      Location:1189
      LUC7; LUC7 N_terminus
    3. XM_063269322.1XP_063125392.1  putative RNA-binding protein Luc7-like 1 isoform X2

      UniProtKB/TrEMBL
      A0A0G2QBZ8
    4. XM_039086289.2XP_038942217.1  putative RNA-binding protein Luc7-like 1 isoform X2

      UniProtKB/TrEMBL
      A0A0G2QBZ8
      Conserved Domains (1) summary
      pfam03194
      Location:1189
      LUC7; LUC7 N_terminus
    5. XM_039086291.2XP_038942219.1  putative RNA-binding protein Luc7-like 1 isoform X3

      UniProtKB/TrEMBL
      A0A0G2QBZ8
      Conserved Domains (1) summary
      cl27291
      Location:1156
      LUC7; LUC7 N_terminus

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001024269.1: Suppressed sequence

      Description
      NM_001024269.1: This RefSeq was removed because currently there is insufficient support for the protein.