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    CB5-B cytochrome B5 isoform B [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817832, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CB5-B
    Official Full Name
    cytochrome B5 isoform B
    Primary source
    TAIR:AT2G32720
    Locus tag
    AT2G32720
    See related
    Araport:AT2G32720
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS CYTOCHROME B5 ISOFORM B; ATCB5-B; B5 #4; CYTB5-D; cytochrome B5 isoform B; F24L7.14; F24L7_14
    Summary
    member of Cytochromes b5
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    Genomic context

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    See CB5-B in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    4
    Sequence:
    Chromosome: 2; NC_003071.7 (13875812..13878710, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene LEUNIG-like protein Neighboring gene Cyclin-dependent kinase inhibitor family protein Neighboring gene 26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit Neighboring gene galactosyltransferase 13

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis sphingolipid fatty acid 2-hydroxylases (AtFAH1 and AtFAH2) are functionally differentiated in fatty acid 2-hydroxylation and stress responses. Nagano M, et al. Plant Physiol, 2012 Jul. PMID 22635113, Free PMC Article
    2. Novel targeting signals mediate the sorting of different isoforms of the tail-anchored membrane protein cytochrome b5 to either endoplasmic reticulum or mitochondria. Hwang YT, et al. Plant Cell, 2004 Nov. PMID 15486098, Free PMC Article
    3. Reconstitution of plant alkane biosynthesis in yeast demonstrates that Arabidopsis ECERIFERUM1 and ECERIFERUM3 are core components of a very-long-chain alkane synthesis complex. Bernard A, et al. Plant Cell, 2012 Jul. PMID 22773744, Free PMC Article
    4. Arabidopsis sucrose transporter SUT4 interacts with cytochrome b5-2 to regulate seed germination in response to sucrose and glucose. Li Y, et al. Mol Plant, 2012 Sep. PMID 22311778
    5. Functional association of cell death suppressor, Arabidopsis Bax inhibitor-1, with fatty acid 2-hydroxylation through cytochrome b₅. Nagano M, et al. Plant J, 2009 Apr. PMID 19054355

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. SUT4 interacts with cytochrome b5-2 to regulate seed germination in response to sucrose and glucose.
      Title: Arabidopsis sucrose transporter SUT4 interacts with cytochrome b5-2 to regulate seed germination in response to sucrose and glucose.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001336411.1
    NM_128831.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables heme binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within alkane biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within very long-chain fatty acid biosynthetic process IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in endoplasmic reticulum HDA PubMed 

    General protein information

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    Preferred Names
    cytochrome B5 isoform B
    NP_180831.1
    • cytochrome B5 isoform B (CB5-B); CONTAINS InterPro DOMAIN/s: Cytochrome b5, heme-binding site (InterPro:IPR018506), Cytochrome b5 (InterPro:IPR001199); BEST Arabidopsis thaliana protein match is: cytochrome B5 isoform D (TAIR:AT5G48810.1); Has 4197 Blast hits to 4166 proteins in 470 species: Archae - 2; Bacteria - 26; Metazoa - 1028; Fungi - 1701; Plants - 800; Viruses - 3; Other Eukaryotes - 637 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      13875812..13878710 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128831.4 → NP_180831.1  cytochrome B5 isoform B [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180831.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O48845, Q0WTX9
      UniProtKB/TrEMBL
      A0A178VXM5, A0A5S9X3C4
      Conserved Domains (1) summary
      pfam00173
      Location:9 → 81
      Cyt-b5; Cytochrome b5-like Heme/Steroid binding domain

    2. NM_001336411.1 → NP_001323464.1  cytochrome B5 isoform B [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AX49
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O48845.1

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