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    GulLO5 D-arabinono-1,4-lactone oxidase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819287, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GulLO5
    Official Full Name
    D-arabinono-1,4-lactone oxidase family protein
    Primary source
    TAIR:AT2G46740
    Locus tag
    AT2G46740
    See related
    Araport:AT2G46740
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    4-lactone ( L -GulL) oxidase 5; AtGulLO5; F19D11.2; L -gulono-1
    Summary
    Encodes a homolog of rat L-gulono-1,4-lactone (L-GulL) oxidase that is involved in the biosynthesis of L-ascorbic acid.
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    Genomic context

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    See GulLO5 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    4
    Sequence:
    Chromosome: 2; NC_003071.7 (19205157..19207608, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene death domain associated protein Neighboring gene D-arabinono-1,4-lactone oxidase family protein Neighboring gene D-arabinono-1,4-lactone oxidase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The contribution of Arabidopsis homologs of L-gulono-1,4-lactone oxidase to the biosynthesis of ascorbic acid. Maruta T, et al. Biosci Biotechnol Biochem, 2010. PMID 20622436
    2. Cell wall proteins in apoplastic fluids of Arabidopsis thaliana rosettes: identification by mass spectrometry and bioinformatics. Boudart G, et al. Proteomics, 2005 Jan. PMID 15593128
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_130240.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables D-arabinono-1,4-lactone oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables FAD binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables L-gulonolactone oxidase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in L-ascorbic acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within L-ascorbic acid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plant-type cell wall HDA PubMed 

    General protein information

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    Preferred Names
    D-arabinono-1,4-lactone oxidase family protein
    NP_182197.1
    • D-arabinono-1,4-lactone oxidase family protein; FUNCTIONS IN: oxidoreductase activity, D-arabinono-1,4-lactone oxidase activity, FAD binding, catalytic activity; INVOLVED IN: oxidation reduction; LOCATED IN: cell wall; EXPRESSED IN: leaf apex, root; CONTAINS InterPro DOMAIN/s: D-arabinono-1,4-lactone oxidase (InterPro:IPR007173), FAD-binding, type 2 (InterPro:IPR016166), Plant-specific FAD-dependent oxidoreductase (InterPro:IPR010030), FAD linked oxidase, N-terminal (InterPro:IPR006094); BEST Arabidopsis thaliana protein match is: D-arabinono-1,4-lactone oxidase family protein (TAIR:AT2G46750.1); Has 2786 Blast hits to 2671 proteins in 804 species: Archae - 14; Bacteria - 1897; Metazoa - 120; Fungi - 214; Plants - 254; Viruses - 0; Other Eukaryotes - 287 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      19205157..19207608 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130240.3 → NP_182197.1  D-arabinono-1,4-lactone oxidase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_182197.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O81030
      UniProtKB/TrEMBL
      A0A178VXG4, A0A5S9X7J5, A0A7G2EKV4
      Conserved Domains (1) summary
      TIGR01677
      Location:33 → 586
      pln_FAD_oxido; plant-specific FAD-dependent oxidoreductase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O81030.1

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