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    PANK1 pantothenate kinase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842339, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PANK1
    Official Full Name
    pantothenate kinase 1
    Primary source
    TAIR:AT1G60440
    Locus tag
    AT1G60440
    See related
    Araport:AT1G60440
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATCOAA; ATPANK1; pantothenate kinase 1; T13D8.31; T13D8_31
    Summary
    The gene AT1G60440 encodes pantothenate kinase 1. Its molecular function was shown to phosphorylate pantothenate to form 4#Aeo-phosphopantothenate.
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    Genomic context

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    See PANK1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    10
    Sequence:
    Chromosome: 1; NC_003070.9 (22266416..22269258, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene DC1 domain-containing protein Neighboring gene ncRNA Neighboring gene actin-related protein C3 Neighboring gene galactinol synthase 7 Neighboring gene uncharacterized protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Plant coenzyme A biosynthesis: characterization of two pantothenate kinases from Arabidopsis. Tilton GB, et al. Plant Mol Biol, 2006 Jul. PMID 16897480
    2. 4'-phosphopantetheine and coenzyme A biosynthesis in plants. Kupke T, et al. J Biol Chem, 2003 Oct 3. PMID 12860978
    3. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001333894.1
    NM_001333895.1
    NM_104731.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pantothenate kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables pantothenate kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within coenzyme A biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in coenzyme A biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    pantothenate kinase 1
    NP_176247.2
    • pantothenate kinase 1 (PANK1); FUNCTIONS IN: pantothenate kinase activity; INVOLVED IN: acetyl-CoA biosynthetic process, coenzyme A biosynthetic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Fumble (InterPro:IPR011602), Eukaryotic pantothenate kinase (InterPro:IPR004567); BEST Arabidopsis thaliana protein match is: pantothenate kinase 2 (TAIR:AT4G32180.3); Has 1272 Blast hits to 1253 proteins in 425 species: Archae - 2; Bacteria - 436; Metazoa - 318; Fungi - 143; Plants - 93; Viruses - 0; Other Eukaryotes - 280 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      22266416..22269258 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104731.5 → NP_176247.2  pantothenate kinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176247.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80765, Q0WNV9, Q66GL8
      UniProtKB/TrEMBL
      A0A5S9WR56
      Conserved Domains (1) summary
      PLN02920
      Location:1 → 383
      PLN02920; pantothenate kinase 1

    2. NM_001333894.1 → NP_001320517.1  pantothenate kinase 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WG63, A0A1P8AN33
      Conserved Domains (1) summary
      cl17037
      Location:8 → 306
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    3. NM_001333895.1 → NP_001320518.1  pantothenate kinase 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AN29, A0A5S9WR56
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O80765.2

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