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    Metallopeptidase M24 family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837451, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Metallopeptidase M24 family protein
    Primary source
    TAIR:AT1G09300
    Locus tag
    AT1G09300
    See related
    Araport:AT1G09300
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T31J12.2; T31J12_2
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    12
    Sequence:
    Chromosome: 1; NC_003070.9 (3003495..3008381)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Chaperone DnaJ-domain superfamily protein Neighboring gene importin alpha isoform 4 Neighboring gene rhodanese-like domain protein Neighboring gene uncharacterized protein Neighboring gene plant/protein (Protein of unknown function, DUF538) Neighboring gene agenet domain-containing protein Neighboring gene golgi apparatus membrane protein-like protein ECHIDNA protein Neighboring gene chloroplast RNA binding protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. INTERMEDIATE CLEAVAGE PEPTIDASE55 Modifies Enzyme Amino Termini and Alters Protein Stability in Arabidopsis Mitochondria. Huang S, et al. Plant Physiol, 2015 Jun. PMID 25862457, Free PMC Article
    2. Identification of cleavage sites and substrate proteins for two mitochondrial intermediate peptidases in Arabidopsis thaliana. Carrie C, et al. J Exp Bot, 2015 May. PMID 25732537, Free PMC Article
    3. AtOMA1 Affects the OXPHOS System and Plant Growth in Contrast to Other Newly Identified ATP-Independent Proteases in Arabidopsis Mitochondria. Migdal I, et al. Front Plant Sci, 2017. PMID 28936218, Free PMC Article
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001123782.1
    NM_100800.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables aminopeptidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables aminopeptidase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables manganese ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metalloaminopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peptidase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein stabilization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Metallopeptidase M24 family protein
    NP_001117254.1
    • Metallopeptidase M24 family protein; FUNCTIONS IN: metallopeptidase activity, manganese ion binding, metalloexopeptidase activity, aminopeptidase activity; INVOLVED IN: proteolysis, cellular process; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M24B, X-Pro dipeptidase/aminopeptidase P N-terminal (InterPro:IPR007865), Peptidase M24, structural domain (InterPro:IPR000994), Peptidase M24, methionine aminopeptidase (InterPro:IPR001714); BEST Arabidopsis thaliana protein match is: Metallopeptidase M24 family protein (TAIR:AT4G29490.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_172401.2
    • Metallopeptidase M24 family protein; FUNCTIONS IN: metallopeptidase activity, manganese ion binding, metalloexopeptidase activity, aminopeptidase activity; INVOLVED IN: proteolysis, cellular process; LOCATED IN: mitochondrion; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M24B, X-Pro dipeptidase/aminopeptidase P N-terminal (InterPro:IPR007865), Peptidase M24, structural domain (InterPro:IPR000994), Peptidase M24, methionine aminopeptidase (InterPro:IPR001714); BEST Arabidopsis thaliana protein match is: Metallopeptidase M24 family protein (TAIR:AT4G29490.1); Has 16476 Blast hits to 16448 proteins in 2755 species: Archae - 330; Bacteria - 11247; Metazoa - 589; Fungi - 576; Plants - 221; Viruses - 0; Other Eukaryotes - 3513 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      3003495..3008381
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001123782.1 → NP_001117254.1  Metallopeptidase M24 family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001117254.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9TG91, A0A654E964
      Conserved Domains (3) summary
      PRK10879
      Location:24 → 430
      PRK10879; proline aminopeptidase P II; Provisional
      cd01087
      Location:186 → 417
      Prolidase; Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on ...
      pfam05195
      Location:26 → 144
      AMP_N; Aminopeptidase P, N-terminal domain

    2. NM_100800.4 → NP_172401.2  Metallopeptidase M24 family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172401.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4HZG9, F4HZH0, Q8GYQ0, Q9ZPZ5, W6HYK5
      UniProtKB/TrEMBL
      A0A5S9TG91, A0A654E964
      Conserved Domains (2) summary
      cd01087
      Location:217 → 448
      Prolidase; Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on ...
      pfam05195
      Location:57 → 173
      AMP_N; Aminopeptidase P, N-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4HZG9.1

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