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    APT2 adenine phosphoribosyl transferase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 844345, updated on 18-Sep-2024

    Summary

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    Official Symbol
    APT2
    Official Full Name
    adenine phosphoribosyl transferase 2
    Primary source
    TAIR:AT1G80050
    Locus tag
    AT1G80050
    See related
    Araport:AT1G80050
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    adenine phosphoribosyl transferase 2; ATAPT2; F18B13.14; F18B13_14; PHT1.1
    Summary
    Encodes an adenosine phosphoribosyl transferase(E.C:2.4.2.7), a constitutively expressed enzyme involved in the one-step salvage of adenine to AMP. This isozyme has high affinity for cytokinins and is likely to be localized to the cytosol.
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    Genomic context

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    See APT2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (30111497..30114010, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Molecular chaperone Hsp40/DnaJ family protein Neighboring gene ubiquitin system component Cue Neighboring gene Ubiquitin-like superfamily protein Neighboring gene Pre-mRNA-processing-splicing factor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The cloning of two Arabidopsis genes belonging to a phosphate transporter family. Smith FW, et al. Plant J, 1997 Jan. PMID 9025304
    2. A second form of adenine phosphoribosyltransferase in Arabidopsis thaliana with relative specificity towards cytokinins. Schnorr KM, et al. Plant J, 1996 Jun. PMID 8696367
    3. Adenine phosphoribosyltransferase isoforms of Arabidopsis and their potential contributions to adenine and cytokinin metabolism. Allen M, et al. Physiol Plant, 2002 May. PMID 12010467
    4. Identification of new intrinsic proteins in Arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2004 Jul. PMID 15060130
    5. Isolation and proteomic characterization of the Arabidopsis Golgi defines functional and novel components involved in plant cell wall biosynthesis. Parsons HT, et al. Plant Physiol, 2012 May. PMID 22430844, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001334951.1
    NM_106654.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables adenine phosphoribosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables adenine phosphoribosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables adenine phosphoribosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables phosphate transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in AMP salvage IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in adenine salvage IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within adenine salvage TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within phosphate ion transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    adenine phosphoribosyl transferase 2
    NP_178122.1
    • adenine phosphoribosyl transferase 2 (APT2); FUNCTIONS IN: phosphate transmembrane transporter activity, adenine phosphoribosyltransferase activity; INVOLVED IN: adenine salvage; LOCATED IN: cytosol, plasma membrane; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Adenine phosphoribosyl transferase (InterPro:IPR005764), Phosphoribosyltransferase (InterPro:IPR000836); BEST Arabidopsis thaliana protein match is: adenine phosphoribosyltransferase 5 (TAIR:AT5G11160.1); Has 8411 Blast hits to 8411 proteins in 2474 species: Archae - 199; Bacteria - 5670; Metazoa - 171; Fungi - 181; Plants - 165; Viruses - 0; Other Eukaryotes - 2025 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      30111497..30114010 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_106654.3 → NP_178122.1  adenine phosphoribosyl transferase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_178122.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39004, Q42563
      UniProtKB/TrEMBL
      A0A178W1K2, A0A5S9WVX8
      Conserved Domains (1) summary
      PLN02293
      Location:1 → 187
      PLN02293; adenine phosphoribosyltransferase

    2. NM_001334951.1 → NP_001320554.1  adenine phosphoribosyl transferase 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AN73, A0A5S9WVX8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q42563.1

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