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    Transmembrane amino acid transporter family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837344, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Transmembrane amino acid transporter family protein
    Primary source
    TAIR:AT1G08230
    Locus tag
    AT1G08230
    See related
    Araport:AT1G08230
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Summary
    Codes for a H+-driven, high affinity gamma-aminobutyric acid (GABA) transporter. Localized at the plasma membrane. In planta, AtGAT1 expression was highest in flowers and under conditions of elevated GABA concentrations such as wounding or senescence.
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    5
    Sequence:
    Chromosome: 1; NC_003070.9 (2583594..2586969, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Eukaryotic aspartyl protease family protein Neighboring gene ATPase complex subunit Neighboring gene tRNA-Gly Neighboring gene arogenate dehydratase 6 Neighboring gene DNA polymerase epsilon catalytic subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. AtGAT1, a high affinity transporter for gamma-aminobutyric acid in Arabidopsis thaliana. Meyer A, et al. J Biol Chem, 2006 Mar 17. PMID 16407306, Free PMC Article
    2. Uncovering Arabidopsis membrane protein interactome enriched in transporters using mating-based split ubiquitin assays and classification models. Chen J, et al. Front Plant Sci, 2012. PMID 22737156, Free PMC Article
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AtGAT1 is a high affinity transporter for gamma-aminobutyric acid in Arabidopsis thaliana. [AtGAT1]
      Title: AtGAT1, a high affinity transporter for gamma-aminobutyric acid in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001084018.3
    NM_001331762.1
    NM_001331763.1
    NM_001331764.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables gamma-aminobutyric acid transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within gamma-aminobutyric acid transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Transmembrane amino acid transporter family protein
    NP_001077487.1
    • Transmembrane amino acid transporter family protein; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Amino acid transporter, transmembrane (InterPro:IPR013057); BEST Arabidopsis thaliana protein match is: Transmembrane amino acid transporter family protein (TAIR:AT5G41800.1); Has 2686 Blast hits to 2681 proteins in 218 species: Archae - 0; Bacteria - 0; Metazoa - 558; Fungi - 296; Plants - 1464; Viruses - 0; Other Eukaryotes - 368 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      2583594..2586969 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001331761.1 → NP_001320802.1  Transmembrane amino acid transporter family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WI04, A0A1P8ANY8

    2. NM_001084018.3 → NP_001077487.1  Transmembrane amino acid transporter family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077487.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4HW02, Q9SGD7
      UniProtKB/TrEMBL
      A0A5S9TA02, A0A654E933
      Conserved Domains (1) summary
      cl00456
      Location:29 → 440
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    3. NM_001331763.1 → NP_001320800.1  Transmembrane amino acid transporter family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WI04, A0A1P8ANX9

    4. NM_001331762.1 → NP_001320801.1  Transmembrane amino acid transporter family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WI04, A0A1P8ANX9

    5. NM_001331764.1 → NP_001320799.1  Transmembrane amino acid transporter family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WI04, A0A1P8ANX9
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4HW02.1

    Gene LinkOut

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