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    GLY3 glyoxalase II 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841793, updated on 18-Sep-2024

    Summary

    Official Symbol
    GLY3
    Official Full Name
    glyoxalase II 3
    Primary source
    TAIR:AT1G53580
    Locus tag
    AT1G53580
    See related
    Araport:AT1G53580
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ETHE1; ETHE1-LIKE; ETHYLMALONIC ENCEPHALOPATHY PROTEIN1; F22G10.9; GLX2-3; GLYOXALASE 2-3; glyoxalase II 3; glyoxalase II 3; T3F20.11; T3F20_11
    Summary
    Mononuclear Fe(II)-containing member of the b-lactamase fold superfamily. ETHE1 is homodimeric in solution, exhibits low-level esterase activity, and specifically binds a single Fe(II) atom in the active site.
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    Genomic context

    See GLY3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Sequence:
    Chromosome: 1; NC_003070.9 (19991271..19993458, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene F-box family protein Neighboring gene Ribosomal protein L18ae family Neighboring gene mitogen-activated protein kinase kinase kinase 3 Neighboring gene Calcium-dependent lipid-binding (CaLB domain) family protein Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    General gene information

    NM_104236.5
    NM_202289.3

    Gene Ontology Provided by TAIR

    General protein information

    Preferred Names
    glyoxalase II 3
    NP_564636.2
    • glyoxalase II 3 (GLY3); FUNCTIONS IN: hydrolase activity, acting on ester bonds, hydroxyacylglutathione hydrolase activity; INVOLVED IN: response to salt stress, methylglyoxal catabolic process to D-lactate; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Beta-lactamase-like (InterPro:IPR001279); BEST Arabidopsis thaliana protein match is: Metallo-hydrolase/oxidoreductase superfamily protein (TAIR:AT3G10850.1); Has 13610 Blast hits to 13607 proteins in 2472 species: Archae - 279; Bacteria - 8978; Metazoa - 399; Fungi - 229; Plants - 189; Viruses - 0; Other Eukaryotes - 3536 (source: NCBI BLink).
    NP_974018.3
    • glyoxalase II 3 (GLY3); FUNCTIONS IN: hydrolase activity, acting on ester bonds, hydroxyacylglutathione hydrolase activity; INVOLVED IN: response to salt stress, methylglyoxal catabolic process to D-lactate; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Beta-lactamase-like (InterPro:IPR001279); BEST Arabidopsis thaliana protein match is: Metallo-hydrolase/oxidoreductase superfamily protein (TAIR:AT3G10850.1); Has 13580 Blast hits to 13577 proteins in 2470 species: Archae - 281; Bacteria - 8959; Metazoa - 398; Fungi - 229; Plants - 189; Viruses - 0; Other Eukaryotes - 3524 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      19991271..19993458 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104236.5 → NP_564636.2  glyoxalase II 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564636.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q93VR2, Q96332, Q9C8L4, Q9LPH3
      UniProtKB/TrEMBL
      A0A5S9WPC7
      Conserved Domains (2) summary
      PLN02962
      Location:51 → 292
      PLN02962; hydroxyacylglutathione hydrolase
      cd07724
      Location:53 → 234
      POD-like_MBL-fold; ETHE1 (PDO type I), persulfide dioxygenase A (PDOA, PDO type II) and related proteins; MBL-fold metallo-hydrolase domain
    2. NM_202289.3 → NP_974018.3  glyoxalase II 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974018.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9WPC7, F4HRK0
      Conserved Domains (2) summary
      PLN02962
      Location:51 → 292
      PLN02962; hydroxyacylglutathione hydrolase
      cd07724
      Location:53 → 234
      POD-like_MBL-fold; ETHE1 (PDO type I), persulfide dioxygenase A (PDOA, PDO type II) and related proteins; MBL-fold metallo-hydrolase domain
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