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    MEE57 DNA (cytosine-5-)-methyltransferase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 826994, updated on 14-Nov-2024

    Summary

    Official Symbol
    MEE57
    Official Full Name
    DNA (cytosine-5-)-methyltransferase family protein
    Primary source
    TAIR:AT4G13610
    Locus tag
    AT4G13610
    See related
    Araport:AT4G13610
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    maternal effect embryo arrest 57; T6G15.160; T6G15_160
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    Genomic context

    See MEE57 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    13
    Sequence:
    Chromosome: 4; NC_003075.7 (7915022..7921231)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Carbohydrate-binding X8 domain superfamily protein Neighboring gene miscRNA Neighboring gene Uncharacterized protein family SERF

    General gene information

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA (cytosine-5-)-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables chromatin binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    DNA (cytosine-5-)-methyltransferase family protein
    NP_193097.1
    • maternal effect embryo arrest 57 (MEE57); FUNCTIONS IN: DNA binding, DNA (cytosine-5-)-methyltransferase activity; INVOLVED IN: DNA methylation, embryo development ending in seed dormancy; LOCATED IN: nucleus; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: DNA (cytosine-5)-methyltransferase 1 (InterPro:IPR017198), DNA methylase, C-5 cytosine-specific (InterPro:IPR001525), Bromo adjacent homology (BAH) domain (InterPro:IPR001025), DNA methylase, C-5 cytosine-specific, active site (InterPro:IPR018117); BEST Arabidopsis thaliana protein match is: DNA methyltransferase 2 (TAIR:AT4G14140.1); Has 6324 Blast hits to 5616 proteins in 1348 species: Archae - 209; Bacteria - 4007; Metazoa - 304; Fungi - 185; Plants - 335; Viruses - 79; Other Eukaryotes - 1205 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      7915022..7921231
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_117435.1NP_193097.1  DNA (cytosine-5-)-methyltransferase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193097.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9T0I1
      UniProtKB/TrEMBL
      A0A654FNT5
      Conserved Domains (4) summary
      cd04708
      Location:783981
      BAH_plantDCM_II; BAH, or Bromo Adjacent Homology domain, second copy present in DNA (Cytosine-5)-methyltransferases (DCM) from plants. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG dinucleotide, has profound effects ...
      cd04712
      Location:618749
      BAH_DCM_I; BAH, or Bromo Adjacent Homology domain, as present in DNA (Cytosine-5)-methyltransferases (DCM) 1. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG dinucleotide, has profound effects on the genome. ...
      pfam12047
      Location:308422
      DNMT1-RFD; Cytosine specific DNA methyltransferase replication foci domain
      cl17173
      Location:9691397
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...