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    EDD1 glycine-tRNA ligase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 823966, updated on 18-Sep-2024

    Summary

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    Official Symbol
    EDD1
    Official Full Name
    glycine-tRNA ligase
    Primary source
    TAIR:AT3G48110
    Locus tag
    AT3G48110
    See related
    Araport:AT3G48110
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    EDD; EMBRYO-DEFECTIVE-DEVELOPMENT 1; GLYCYL-TRNA SYNTHETASE
    Summary
    glycine-tRNA ligase
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    Genomic context

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    See EDD1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    33
    Sequence:
    Chromosome: 3; NC_003074.8 (17762970..17771146)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene response regulator 5 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene serine/arginine-rich splicing factor Neighboring gene uncharacterized protein Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Inactivation of a glycyl-tRNA synthetase leads to an arrest in plant embryo development. Uwer U, et al. Plant Cell, 1998 Aug. PMID 9707529, Free PMC Article
    2. The Arabidopsis organelle-localized glycyl-tRNA synthetase encoded by EMBRYO DEFECTIVE DEVELOPMENT1 is required for organ patterning. Moschopoulos A, et al. J Exp Bot, 2012 Sep. PMID 22791832, Free PMC Article
    3. Dual targeting is the rule for organellar aminoacyl-tRNA synthetases in Arabidopsis thaliana. Duchêne AM, et al. Proc Natl Acad Sci U S A, 2005 Nov 8. PMID 16251277, Free PMC Article
    4. Requirement of aminoacyl-tRNA synthetases for gametogenesis and embryo development in Arabidopsis. Berg M, et al. Plant J, 2005 Dec. PMID 16297076
    5. The oligomeric stromal proteome of Arabidopsis thaliana chloroplasts. Peltier JB, et al. Mol Cell Proteomics, 2006 Jan. PMID 16207701

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_114680.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables glycine-tRNA ligase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein dimerization activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryo development ending in seed dormancy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within glycyl-tRNA aminoacylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast stroma HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glycine-tRNA ligase
    NP_190394.3
    • EMBRYO-DEFECTIVE-DEVELOPMENT 1 (EDD1); FUNCTIONS IN: glycine-tRNA ligase activity; INVOLVED IN: regulation of embryonic development, glycyl-tRNA aminoacylation, embryo development ending in seed dormancy; LOCATED IN: mitochondrion, chloroplast stroma, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Glycyl-tRNA synthetase, class IIc, beta subunit, N-terminal (InterPro:IPR002311), Glycyl-tRNA synthetase, class II, heterodimeric (InterPro:IPR006194), Glycyl-tRNA synthetase, class IIc, beta subunit (InterPro:IPR015944), Glycyl-tRNA synthetase, class IIc, alpha subunit (InterPro:IPR002310); Has 11308 Blast hits to 11293 proteins in 1754 species: Archae - 4; Bacteria - 6864; Metazoa - 4; Fungi - 1; Plants - 40; Viruses - 0; Other Eukaryotes - 4395 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      17762970..17771146
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_114680.4 → NP_190394.3  glycine-tRNA ligase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190394.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23150, Q8L785, Q9SU73
      UniProtKB/TrEMBL
      A0A178VHQ7, A0A5S9XIT8
      Conserved Domains (3) summary
      PRK14908
      Location:70 → 1064
      PRK14908; glycyl-tRNA synthetase; Provisional
      pfam02091
      Location:73 → 348
      tRNA-synt_2e; Glycyl-tRNA synthetase alpha subunit
      pfam02092
      Location:386 → 928
      tRNA_synt_2f; Glycyl-tRNA synthetase beta subunit
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8L785.1

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