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    GSA2 glutamate-1-semialdehyde 2,1-aminomutase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824034, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GSA2
    Official Full Name
    glutamate-1-semialdehyde 2,1-aminomutase 2
    Primary source
    TAIR:AT3G48730
    Locus tag
    AT3G48730
    See related
    Araport:AT3G48730
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    1-aminomutase 2; glutamate-1-semialdehyde 2
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    Genomic context

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    See GSA2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    4
    Sequence:
    Chromosome: 3; NC_003074.8 (18049571..18051778)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene DEK domain-containing chromatin associated protein Neighboring gene HXXXD-type acyl-transferase family protein Neighboring gene Nodulin MtN3 family protein Neighboring gene tRNA-Gln

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mutations in Plastidial 5-Aminolevulinic Acid Biosynthesis Genes Suppress a Pleiotropic Defect in Shoot Development of a Mitochondrial GABA Shunt Mutant in Arabidopsis. Toyokura K, et al. Plant Cell Physiol, 2015 Jun. PMID 25840087
    2. Light regulation of chlorophyll biosynthesis at the level of 5-aminolevulinate formation in Arabidopsis. Ilag LL, et al. Plant Cell, 1994 Feb. PMID 7908550, Free PMC Article
    3. The oligomeric stromal proteome of Arabidopsis thaliana chloroplasts. Peltier JB, et al. Mol Cell Proteomics, 2006 Jan. PMID 16207701
    4. Quantitative proteomics of a chloroplast SRP54 sorting mutant and its genetic interactions with CLPC1 in Arabidopsis. Rutschow H, et al. Plant Physiol, 2008 Sep. PMID 18633119, Free PMC Article
    5. Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis. Froehlich JE, et al. J Proteome Res, 2003 Jul-Aug. PMID 12938931

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_114732.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables glutamate-1-semialdehyde 2,1-aminomutase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein homodimerization activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables pyridoxal phosphate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables transaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in chlorophyll biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within porphyrin-containing compound biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in protoporphyrinogen IX biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast envelope HDA PubMed 
    located_in chloroplast stroma HDA PubMed 
    located_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    glutamate-1-semialdehyde 2,1-aminomutase 2
    NP_190442.1
    • glutamate-1-semialdehyde 2,1-aminomutase 2 (GSA2); FUNCTIONS IN: glutamate-1-semialdehyde 2,1-aminomutase activity, pyridoxal phosphate binding, transaminase activity, catalytic activity; INVOLVED IN: porphyrin biosynthetic process; LOCATED IN: chloroplast stroma, chloroplast, chloroplast envelope; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Aminotransferase class-III (InterPro:IPR005814), Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase (InterPro:IPR004639), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421); BEST Arabidopsis thaliana protein match is: glutamate-1-semialdehyde-2,1-aminomutase (TAIR:AT5G63570.1); Has 34778 Blast hits to 34772 proteins in 2825 species: Archae - 734; Bacteria - 23568; Metazoa - 533; Fungi - 800; Plants - 388; Viruses - 10; Other Eukaryotes - 8745 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      18049571..18051778
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_114732.5 → NP_190442.1  glutamate-1-semialdehyde 2,1-aminomutase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190442.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q1JPM9, Q42522, Q9SMM6
      UniProtKB/TrEMBL
      A0A178VHC7, A0A5S9XJR1
      Conserved Domains (1) summary
      PLN02482
      Location:1 → 472
      PLN02482; glutamate-1-semialdehyde 2,1-aminomutase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q42522.2

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