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    TON1B tonneau 1b (TON1b) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824666, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TON1B
    Official Full Name
    tonneau 1b (TON1b)
    Primary source
    TAIR:AT3G55005
    Locus tag
    AT3G55005
    See related
    Araport:AT3G55005
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    tonneau 1b
    Summary
    Encodes a protein of unknown function that is involved in cortical microtubule organization. Mutants exhibit abnormal cell growth and patterns of division. TON1B appears to be redundant with TON1A. Encodes a novel protein that is similar to human FOP and OFD1 centrosomal proteins. Localizes to the preprophase band, cytoplasm and cell cortex where it is probably associated with the cortical cytoskeleton. TON1B associates with plant centrin CEN1.
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    Genomic context

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    See TON1B in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    7
    Sequence:
    Chromosome: 3; NC_003074.8 (20383896..20386452)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene Integrase-type DNA-binding superfamily protein Neighboring gene tonneau family protein Neighboring gene phosphoribosylformylglycinamidine cyclo-ligase, chloroplast / phosphoribosyl-aminoimidazole synthetase / AIR synthase (PUR5) Neighboring gene Ypt/Rab-GAP domain of gyp1p superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis TRM1-TON1 interaction reveals a recruitment network common to plant cortical microtubule arrays and eukaryotic centrosomes. Drevensek S, et al. Plant Cell, 2012 Jan. PMID 22286137, Free PMC Article
    2. Arabidopsis TONNEAU1 proteins are essential for preprophase band formation and interact with centrin. Azimzadeh J, et al. Plant Cell, 2008 Aug. PMID 18757558, Free PMC Article
    3. Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics. Kim TW, et al. Plant Cell, 2023 Mar 15. PMID 36660928, Free PMC Article
    4. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data show that TRM1 interacts in vivo with TON1 and is able to target TON1 to cortical microtubules via its C-terminal TON1 interaction motif.
      Title: The Arabidopsis TRM1-TON1 interaction reveals a recruitment network common to plant cortical microtubule arrays and eukaryotic centrosomes.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_115358.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cortical cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in microtubule cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within microtubule cytoskeleton organization NAS
    Non-traceable Author Statement
    more info
    		  
    involved_in preprophase band assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cortical microtubule cytoskeleton IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    tonneau 1b (TON1b)
    NP_567013.1
    • tonneau 1b (TON1B); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: microtubule cytoskeleton organization; LOCATED IN: plasma membrane, microsome; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: LisH dimerisation motif (InterPro:IPR006594); BEST Arabidopsis thaliana protein match is: tonneau family protein (TAIR:AT3G55000.1); Has 213 Blast hits to 211 proteins in 69 species: Archae - 0; Bacteria - 0; Metazoa - 114; Fungi - 0; Plants - 64; Viruses - 0; Other Eukaryotes - 35 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      20383896..20386452
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115358.5 → NP_567013.1  tonneau 1b (TON1b) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567013.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FQ23, Q9FQ24, Q9SV48
      UniProtKB/TrEMBL
      A0A5S9XL21, A0A654FFW3
      Conserved Domains (2) summary
      pfam09398
      Location:61 → 137
      FOP_dimer; FOP N terminal dimerization domain
      pfam16045
      Location:77 → 104
      LisH_2; LisH
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FQ24.1

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