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    eIF6A Translation initiation factor IF6 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824728, updated on 18-Sep-2024

    Summary

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    Official Symbol
    eIF6A
    Official Full Name
    Translation initiation factor IF6
    Primary source
    TAIR:AT3G55620
    Locus tag
    AT3G55620
    See related
    Araport:AT3G55620
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    emb1624; embryo defective 1624; eukaryotic initiation facor 6A
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    Genomic context

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    See eIF6A in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    8
    Sequence:
    Chromosome: 3; NC_003074.8 (20634057..20636555)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Membrane fusion protein Use1 Neighboring gene Mitochondrial glycoprotein family protein Neighboring gene delta 1-pyrroline-5-carboxylate synthase 2 Neighboring gene DHFS-FPGS homolog D Neighboring gene Mitochondrial substrate carrier family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Involvement of Arabidopsis RACK1 in protein translation and its regulation by abscisic acid. Guo J, et al. Plant Physiol, 2011 Jan. PMID 21098678, Free PMC Article
    2. The RING E3 Ligase KEEP ON GOING Modulates JASMONATE ZIM-DOMAIN12 Stability. Pauwels L, et al. Plant Physiol, 2015 Oct. PMID 26320228, Free PMC Article
    3. Proteomic analysis of the Arabidopsis nucleolus suggests novel nucleolar functions. Pendle AF, et al. Mol Biol Cell, 2005 Jan. PMID 15496452, Free PMC Article
    4. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    5. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_115420.4

    Gene Ontology Provided by TAIR

    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to abscisic acid stimulus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within embryo development ending in seed dormancy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within embryo development ending in seed dormancy NAS
    Non-traceable Author Statement
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleolus HDA PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Translation initiation factor IF6
    NP_191121.1
    • embryo defective 1624 (emb1624); FUNCTIONS IN: ribosome binding, translation initiation factor activity; INVOLVED IN: translational initiation, embryo development ending in seed dormancy; LOCATED IN: nucleolus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Translation initiation factor IF6 (InterPro:IPR002769); BEST Arabidopsis thaliana protein match is: Translation initiation factor IF6 (TAIR:AT2G39820.1); Has 941 Blast hits to 941 proteins in 349 species: Archae - 255; Bacteria - 0; Metazoa - 235; Fungi - 146; Plants - 134; Viruses - 0; Other Eukaryotes - 171 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      20634057..20636555
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115420.4 → NP_191121.1  Translation initiation factor IF6 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191121.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M060
      UniProtKB/TrEMBL
      A0A178VEN3, A0A5S9XL42
      Conserved Domains (1) summary
      PTZ00136
      Location:1 → 244
      PTZ00136; eukaryotic translation initiation factor 6-like protein; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M060.1

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