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    SLD1 Fatty acid/sphingolipid desaturase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825331, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SLD1
    Official Full Name
    Fatty acid/sphingolipid desaturase
    Primary source
    TAIR:AT3G61580
    Locus tag
    AT3G61580
    See related
    Araport:AT3G61580
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtSLD1; sphingoid LCB desaturase 1
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    Genomic context

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    See SLD1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    1
    Sequence:
    Chromosome: 3; NC_003074.8 (22786022..22787972)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Reticulon family protein Neighboring gene GRIP-related ARF-binding domain-containing protein 1 Neighboring gene uncharacterized protein Neighboring gene Galactose oxidase/kelch repeat superfamily protein Neighboring gene POZ/BTB containin G-protein 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A sphingolipid desaturase from higher plants. Identification of a new cytochrome b5 fusion protein. Sperling P, et al. J Biol Chem, 1998 Oct 30. PMID 9786850
    2. Sphingolipid Δ8 unsaturation is important for glucosylceramide biosynthesis and low-temperature performance in Arabidopsis. Chen M, et al. Plant J, 2012 Mar. PMID 22023480
    3. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    4. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_116023.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables sphingolipid 8-(E/Z)-desaturase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to cold IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within lipid metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in sphingolipid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Fatty acid/sphingolipid desaturase
    NP_191717.1
    • Fatty acid/sphingolipid desaturase; CONTAINS InterPro DOMAIN/s: Fatty acid desaturase, type 1 (InterPro:IPR005804), Fatty acid/sphingolipid desaturase (InterPro:IPR012171), Cytochrome b5 (InterPro:IPR001199); BEST Arabidopsis thaliana protein match is: Fatty acid/sphingolipid desaturase (TAIR:AT2G46210.1); Has 5416 Blast hits to 5306 proteins in 857 species: Archae - 2; Bacteria - 1062; Metazoa - 955; Fungi - 1609; Plants - 915; Viruses - 2; Other Eukaryotes - 871 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      22786022..22787972
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_116023.2 → NP_191717.1  Fatty acid/sphingolipid desaturase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191717.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LB96, Q9ZRP7
      UniProtKB/TrEMBL
      A0A178V7U9, A0A5S9XN41
      Conserved Domains (2) summary
      cd03506
      Location:143 → 404
      Delta6-FADS-like; The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases ...
      pfam00173
      Location:11 → 82
      Cyt-b5; Cytochrome b5-like Heme/Steroid binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZRP7.1

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