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    MOS11 Protein MODIFIER OF SNC1 11 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831253, updated on 23-Oct-2024

    Summary

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    Official Symbol
    MOS11
    Official Full Name
    Protein MODIFIER OF SNC1 11
    Primary source
    TAIR:AT5G02770
    Locus tag
    AT5G02770
    See related
    Araport:AT5G02770
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    11; F9G14.80; F9G14_80; modifier of snc1
    Summary
    Encodes a conserved eukaryotic protein with homology to the human RNA binding protein CIP29 that localizes to the nucleus. Mutants accumulate more poly(A) mRNAs in the nucleus, likely resulting from reduced mRNA export activity.
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    Genomic context

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    See MOS11 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (627034..629280, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene RING/U-box superfamily protein Neighboring gene ncRNA Neighboring gene Protein phosphatase 2C family protein Neighboring gene glutathione transferase lambda 1 Neighboring gene Glutathione S-transferase family protein Neighboring gene Protein kinase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis mRNA export factor MOS11: molecular interactions and role in abiotic stress responses. Rödel A, et al. New Phytol, 2024 Jul. PMID 38650347
    2. MOS11: a new component in the mRNA export pathway. Germain H, et al. PLoS Genet, 2010 Dec 23. PMID 21203492, Free PMC Article
    3. The Arabidopsis THO/TREX component TEX1 functionally interacts with MOS11 and modulates mRNA export and alternative splicing events. Sørensen BB, et al. Plant Mol Biol, 2017 Feb. PMID 28004241
    4. Arabidopsis DEAD-box RNA helicase UAP56 interacts with both RNA and DNA as well as with mRNA export factors. Kammel C, et al. PLoS One, 2013. PMID 23555998, Free PMC Article
    5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Arabidopsis mRNA export factor MOS11: molecular interactions and role in abiotic stress responses.
      Title: Arabidopsis mRNA export factor MOS11: molecular interactions and role in abiotic stress responses.
    2. Arabidopsis TEX1 and MOS11 are involved in distinct steps of the biogenesis of mRNAs and small RNAs, and that they interact regarding some aspects, but act independently in others.
      Title: The Arabidopsis THO/TREX component TEX1 functionally interacts with MOS11 and modulates mRNA export and alternative splicing events.
    3. MOS11 (At5g02770) is a new component for mRNA export.
      Title: MOS11: a new component in the mRNA export pathway.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_120355.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within poly(A)+ mRNA export from nucleus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Protein MODIFIER OF SNC1 11
    NP_195897.1
    • unknown protein; Has 469 Blast hits to 336 proteins in 126 species: Archae - 0; Bacteria - 54; Metazoa - 249; Fungi - 22; Plants - 47; Viruses - 0; Other Eukaryotes - 97 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      627034..629280 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120355.3 → NP_195897.1  Protein MODIFIER OF SNC1 11 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195897.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LZ08
      UniProtKB/TrEMBL
      A0A5S9Y0T3, A0A654FXQ3
      Conserved Domains (2) summary
      PTZ00121
      Location:45 → 213
      PTZ00121; MAEBL; Provisional
      pfam18592
      Location:78 → 111
      Tho1_MOS11_C; Tho1/MOS11 C-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LZ08.1

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