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    NUDT8 nudix hydrolase homolog 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834771, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NUDT8
    Official Full Name
    nudix hydrolase homolog 8
    Primary source
    TAIR:AT5G47240
    Locus tag
    AT5G47240
    See related
    Araport:AT5G47240
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    atnudt8; MQL5.10; MQL5_10; nudix hydrolase homolog 8
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    Genomic context

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    See NUDT8 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    6
    Sequence:
    Chromosome: 5; NC_003076.8 (19183523..19185644)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ethylene responsive element binding factor 5 Neighboring gene ncRNA Neighboring gene LRR and NB-ARC domains-containing disease resistance protein Neighboring gene putative disease resistance protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional characterization of a Nudix hydrolase AtNUDX8 upon pathogen attack indicates a positive role in plant immune responses. Fonseca JP, et al. PLoS One, 2014. PMID 25436909, Free PMC Article
    2. Comprehensive analysis of cytosolic Nudix hydrolases in Arabidopsis thaliana. Ogawa T, et al. J Biol Chem, 2005 Jul 1. PMID 15878881
    3. A downstream mediator in the growth repression limb of the jasmonate pathway. Yan Y, et al. Plant Cell, 2007 Aug. PMID 17675405, Free PMC Article
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Nudix hydrolase 8 is involved in plant immunity as a positive regulator of defense in Arabidopsis.
      Title: Functional characterization of a Nudix hydrolase AtNUDX8 upon pathogen attack indicates a positive role in plant immune responses.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_124095.4

    Gene Ontology Provided by TAIR

    Process Evidence Code Pubs
    acts_upstream_of_or_within response to wounding IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nudix hydrolase homolog 8
    NP_568680.1
    • nudix hydrolase homolog 8 (NUDT8); FUNCTIONS IN: hydrolase activity; INVOLVED IN: response to wounding; LOCATED IN: cytosol; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: NUDIX hydrolase domain-like (InterPro:IPR015797), NUDIX hydrolase, conserved site (InterPro:IPR020084), Nudix hydrolase 6-like (InterPro:IPR003293), NUDIX hydrolase domain (InterPro:IPR000086); BEST Arabidopsis thaliana protein match is: nudix hydrolase homolog 2 (TAIR:AT5G47650.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      19183523..19185644
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001344713.1 → NP_001331621.1  nudix hydrolase homolog 8 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BEI5, A0A7G2FE68

    2. NM_124095.4 → NP_568680.1  nudix hydrolase homolog 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568680.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8L7W2, Q8LAJ0, Q9LVT5
      UniProtKB/TrEMBL
      A0A5S9YBU1, A0A7G2FE68
      Conserved Domains (2) summary
      cd04670
      Location:189 → 320
      Nudix_Hydrolase_12; Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly ...
      pfam18290
      Location:96 → 175
      Nudix_hydro; Nudix hydrolase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8L7W2.2

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