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    PAL3 phenyl alanine ammonia-lyase 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830302, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PAL3
    Official Full Name
    phenyl alanine ammonia-lyase 3
    Primary source
    TAIR:AT5G04230
    Locus tag
    AT5G04230
    See related
    Araport:AT5G04230
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATPAL3; F21E1.150; F21E1_150; phenyl alanine ammonia-lyase 3
    Summary
    Member of Phenylalanine ammonialyase (PAL) gene family. Differs significantly from PAL1 and PAL2 and other sequenced plant PAL genes. Arabidopsis has four PALs: AT2G37040 (PAL1), AT3G53260 (PAL2), AT5G04230 (PAL3) and AT3G10340 (PAL4).
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    Genomic context

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    See PAL3 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    3
    Sequence:
    Chromosome: 5; NC_003076.8 (1160569..1163957)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene CCCH-type zinc fingerfamily protein with RNA-binding domain-containing protein Neighboring gene Calcium-dependent lipid-binding (CaLB domain) family protein Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene Zinc finger (C2H2 type) family protein / transcription factor jumonji (jmj) family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The phenylalanine ammonia-lyase gene family in Arabidopsis thaliana. Wanner LA, et al. Plant Mol Biol, 1995 Jan. PMID 7888622
    2. Arabidopsis Kelch repeat F-box proteins regulate phenylpropanoid biosynthesis via controlling the turnover of phenylalanine ammonia-lyase. Zhang X, et al. Plant Cell, 2013 Dec. PMID 24363316, Free PMC Article
    3. Down-regulation of Kelch domain-containing F-box protein in Arabidopsis enhances the production of (poly)phenols and tolerance to ultraviolet radiation. Zhang X, et al. Plant Physiol, 2015 Feb. PMID 25502410, Free PMC Article
    4. Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics. Kim TW, et al. Plant Cell, 2023 Mar 15. PMID 36660928, Free PMC Article
    5. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001203294.1
    NM_120505.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables phenylalanine ammonia-lyase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cinnamic acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within defense response TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within response to wounding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    phenyl alanine ammonia-lyase 3
    NP_001190223.1
    • phenyl alanine ammonia-lyase 3 (PAL3); FUNCTIONS IN: phenylalanine ammonia-lyase activity; INVOLVED IN: response to wounding, defense response; LOCATED IN: cytoplasm; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Phenylalanine/histidine ammonia-lyase (InterPro:IPR001106), Phenylalanine/histidine ammonia-lyases, active site (InterPro:IPR022313), L-Aspartase-like (InterPro:IPR008948), Phenylalanine ammonia-lyase (InterPro:IPR005922); BEST Arabidopsis thaliana protein match is: phenylalanine ammonia-lyase 4 (TAIR:AT3G10340.1).
    NP_196043.2
    • phenyl alanine ammonia-lyase 3 (PAL3); FUNCTIONS IN: phenylalanine ammonia-lyase activity; INVOLVED IN: response to wounding, defense response; LOCATED IN: cytoplasm; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Phenylalanine/histidine ammonia-lyase (InterPro:IPR001106), Phenylalanine/histidine ammonia-lyases, active site (InterPro:IPR022313), L-Aspartase-like (InterPro:IPR008948), Phenylalanine ammonia-lyase (InterPro:IPR005922); BEST Arabidopsis thaliana protein match is: phenylalanine ammonia-lyase 4 (TAIR:AT3G10340.1); Has 4848 Blast hits to 4828 proteins in 1399 species: Archae - 40; Bacteria - 2936; Metazoa - 80; Fungi - 127; Plants - 1170; Viruses - 0; Other Eukaryotes - 495 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      1160569..1163957
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120505.4 → NP_196043.2  phenyl alanine ammonia-lyase 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196043.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P45725, Q53YP2, Q9FYD8
      UniProtKB/TrEMBL
      A0A178ULH7, A0A5S9Y3H1
      Conserved Domains (2) summary
      PLN02457
      Location:9 → 694
      PLN02457; phenylalanine ammonia-lyase
      pfam00221
      Location:49 → 530
      Lyase_aromatic; Aromatic amino acid lyase

    2. NM_001203294.1 → NP_001190223.1  phenyl alanine ammonia-lyase 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190223.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178ULH7, A0A5S9Y3H1, F4JW69
      Conserved Domains (2) summary
      PLN02457
      Location:9 → 698
      PLN02457; phenylalanine ammonia-lyase
      pfam00221
      Location:49 → 534
      Lyase_aromatic; Aromatic amino acid lyase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P45725.3

    Gene LinkOut

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