U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    VIT1 vacuolar iron transporter 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 814708, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    VIT1
    Official Full Name
    vacuolar iron transporter 1
    Primary source
    TAIR:AT2G01770
    Locus tag
    AT2G01770
    See related
    Araport:AT2G01770
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATVIT1; T8O11.6; T8O11_6; vacuolar iron transporter 1
    Summary
    Encodes an iron transporter required for iron sequestration into vacuoles. Expressed in developing embryo and seed. Localized in the vacuolar membrane.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See VIT1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    4
    Sequence:
    Chromosome: 2; NC_003071.7 (334663..336462, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene microtubule-associated proteins 70-3 Neighboring gene uncharacterized protein Neighboring gene response regulator 14 Neighboring gene Curculin-like (mannose-binding) lectin family protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Overexpression of Arabidopsis VIT1 increases accumulation of iron in cassava roots and stems. Narayanan N, et al. Plant Sci, 2015 Nov. PMID 26475197
    2. Localization of iron in Arabidopsis seed requires the vacuolar membrane transporter VIT1. Kim SA, et al. Science, 2006 Nov 24. PMID 17082420
    3. Vacuolar-Iron-Transporter1-Like proteins mediate iron homeostasis in Arabidopsis. Gollhofer J, et al. PLoS One, 2014. PMID 25360591, Free PMC Article
    4. Trans-Golgi network-located AP1 gamma adaptins mediate dileucine motif-directed vacuolar targeting in Arabidopsis. Wang X, et al. Plant Cell, 2014 Oct. PMID 25351491, Free PMC Article
    5. Identification of the endodermal vacuole as the iron storage compartment in the Arabidopsis embryo. Roschzttardtz H, et al. Plant Physiol, 2009 Nov. PMID 19726572, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables iron ion transmembrane transporter activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables manganese ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular iron ion homeostasis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in intracellular iron ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in intracellular manganese ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within multicellular organismal-level iron ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in vacuolar membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    vacuolar iron transporter 1
    NP_178286.1
    • vacuolar iron transporter 1 (VIT1); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF125, transmembrane (InterPro:IPR008217); Has 1947 Blast hits to 1945 proteins in 688 species: Archae - 106; Bacteria - 1196; Metazoa - 0; Fungi - 163; Plants - 191; Viruses - 0; Other Eukaryotes - 291 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      334663..336462 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_126238.3 → NP_178286.1  vacuolar iron transporter 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_178286.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9ZUA5
      UniProtKB/TrEMBL
      A0A178VRP6, A0A5S9WWP4, A0A654ESP7
      Conserved Domains (1) summary
      cd02435
      Location:14 → 248
      CCC1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZUA5.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools